Peptides with antimicrobial activity, drug compositions for the treatment and prophylaxis of animals, compositions for the treatment and prophylaxis of plants, uses of said peptides, and uses of paenibacillus elgil ourofinensis extract

Abstract

The present invention provides extracts of material fermented with Paenibacillus sp., preferably the one called here Paenibacillus elgii ourofinensis with antimicrobial activity and/or growth promoter in animals intended for slaughter for human consumption. The invention provides new peptides derived from the fractions of the fermentation of Paenibacillus elgii ourofinensis extract, said new peptides having antimicrobial activity and promoting the growth of organisms, for example, plants and animals. The invention is also related to the use of the extract of this new strain, Paenibacillus elgii ourofinensis , as a growth promoter and as an antimicrobial agent in the treatment and prophylaxis of animals intended for human consumption.

1 . A process of obtaining an extract with lipopeptides comprising fermenting  Paenibacillus  and extracting at least one of the following compounds: 
       
         
           
           
               
               
           
         
       
     
     
         2 . A process according to  claim 1 , wherein said  Paenibacillus  is  Paenibacillus elgii  and/or  Paenibacillus elgii ourofinensis.    
     
     
         3 . A bacterial extract of  Paenibacillus  comprising at least one of the following compounds: 
       
         
           
           
               
               
           
         
       
     
     
         4 . A lipopeptide isolated with antimicrobial activity and/or growth promoter comprising at least one of the following compounds: 
       
         
           
           
               
               
           
         
       
     
     
         5 . A drug composition for treatment and/or prophylaxis of animals comprising the lipopeptide of  claim 4 :
 a pharmaceutically acceptable carrier or excipient.   
     
     
         6 . A composition according to  claim 5 , comprising extracts of material fermented with  Paenibacillus.    
     
     
         7 . A composition according to  claim 6 , wherein said  Paenibacillus  is  Paenibacillus elgii  and/or  Paenibacillus elgii ourofinensis.    
     
     
         8 . A drug composition for treatment and/or prophylaxis of animals comprising the bacterial extract of  Paenibacillus  of  claim 3  and:
 a pharmaceutically acceptable carrier or excipient. 
 
     
     
         9 . A composition according to  claim 8 , wherein said  Paenibacillus  is  Paenibacillus elgii  and/or  Paenibacillus elgii ourofinensis.    
     
     
         10 . A composition for the prophylaxis and treatment of plants comprising the lipopeptide of  claim 4  and
 an agriculturally acceptable carrier or substrate. 
 
     
     
         11 . A composition according to  claim 10 , comprising extracts of material fermented with  Paenibacillus.    
     
     
         12 . A composition according to  claim 11 , wherein said  Paenibacillus  is  Paenibacillus elgii  and/or  Paenibacillus elgii ourofinensis.    
     
     
         13 . A method of treatment or prophylaxis of animals intended for human consumption, the method comprising the use of at least one of the lipopeptides of  claim 4   as a growth promoter or antimicrobial agent.   
     
     
         14 . A method for the treatment or prophylaxis of infections caused by phytopathogens in plants, the method comprising the use of at least one of the lipopeptides of  claim 4   as a growth promoter or antimicrobial agent.   
     
     
         15 . A method for the treatment or prophylaxis of conditions involving infections in animals or plants, the method comprising the use of at least one of the lipopeptides of  claim 4   as a growth promoter or antimicrobial agent.