US2014066383A1PendingUtilityA1

Methods of treating cancer

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Assignee: ENDOCTYE INCPriority: Nov 12, 2010Filed: Mar 13, 2013Published: Mar 6, 2014
Est. expiryNov 12, 2030(~4.3 yrs left)· nominal 20-yr term from priority
Inventors:Joseph Anand ReddyChristopher Paul LeamonBinh Nguyen
A61K 38/08A61P 35/00A61P 43/00A61P 15/00A61P 11/00A61K 31/282A61K 31/519A61K 31/4745A61K 31/337A61K 45/06A61K 31/7068A61K 31/517A61K 31/704A61K 47/50A61K 39/3955A61K 33/243G01N 33/575
63
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Claims

Abstract

Described are methods and compositions for treating epithelial tumors with a folate-vinca conjugate in combination with at least one other chemotherapeutic agent in which the tumors include ovarian, endometrial or non-small cell lung cancer tumors, including platinum-resistant ovarian tumors and platinum-sensitive ovarian tumors.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of treatment of a platinum-resistant ovarian cancer, the method comprising the steps of
 administering EC145 to a patient; and   administering to the patient paclitaxel having a mode of action of mitosis inhibition in an effective amount ranging from about 1 μg/m 2  to about 300 mg/m 2  of body surface area.

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