US2014057351A1PendingUtilityA1

Ideotypically modulated pharmacoeffectors for selective cell treatment

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Assignee: IMPERIUM BIOTECHNOLOGIES INCPriority: May 31, 2010Filed: Aug 26, 2013Published: Feb 27, 2014
Est. expiryMay 31, 2030(~3.8 yrs left)· nominal 20-yr term from priority
Inventors:Jacob Jennings Orme
A61P 37/06A61P 31/16A61P 35/02A61P 31/10A61P 31/12A61P 37/02A61P 31/18A61P 37/00A61P 33/10A61P 33/00A61P 3/10A61P 31/14A61P 35/00A61P 31/04A61P 19/02C12N 5/0602A61K 38/4873C07K 16/12C07K 16/30C07K 16/20C07K 16/28C07K 16/08C12N 15/09A61K 48/00C12N 15/63
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Claims

Abstract

In a method embodiment, a method includes introducing a plurality of Ideotypically Modulated Pharmacoeffectors (IMP) into a population of cells. Each IMP may include a detection domain and an activation domain. One or more epitopes is bound by the detection domain. The activation domain is activated in response to the binding. Applications may include but are not limited to viral infections, other intracellular infections, cancers, vector-borne diseases, autoimmune diseases, cellular diseases, cellular enhancement, and research.

Claims

exact text as granted — not AI-modified
1 . A method comprising:
 introducing, into a population of cells, instructions for the manufacture of a plurality of Ideotypically Modulated Pharmacoeffectors (IMPs), each of the plurality of manufactured IMPs comprising:   a detection domain that has affinity for an epitope, and   an activation domain coupled to the detection domain;   wherein the detection domain of each IMP of a subset of the plurality of manufactured IMPs is configured to bind to one or more epitopes; and   
       wherein the activation domain of each IMP of the subset of the plurality of manufactured IMPs is configured to activate and cause a downstream effect in a population of cells. 
     
     
         2 - 29 . (canceled)

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