Method and System for Providing Calibration of an Analyte Sensor in an Analyte Monitoring System

Abstract

Method and apparatus for providing calibration of analyte sensor including applying a control signal, detecting a measured response to the control signal, determining a variance in the detected measured response, and estimating a sensor sensitivity based on the variance in the detected measured response is provided

1 . (canceled) 
     
     
         2 . A method for determining a property of a continuous analyte sensor, the method comprising:
 applying a bias voltage to an analyte sensor;   applying a voltage step above the bias voltage to the analyte sensor;   measuring, using sensor electronics, a signal response of the voltage step;   determining, using the sensor electronics, a peak current of the signal response; and   determining, using the sensor electronics, a property of the sensor by correlating the peak current to a predetermined relationship.   
     
     
         3 . The method of  claim 2 , wherein correlating the peak current to the predetermined relationship comprises calculating an impedance of the sensor based on the peak current and correlating the sensor impedance to the predetermined relationship. 
     
     
         4 . The method of  claim 2 , wherein the property of the sensor is a sensitivity of the sensor or a temperature of the sensor. 
     
     
         5 . The method of  claim 2 , wherein the peak current is a difference between a magnitude of the response prior to the voltage step and a magnitude of the largest measured response resulting from the voltage step. 
     
     
         6 . The method of  claim 2 , wherein the predetermined relationship is an impedance-to-sensor sensitivity relationship, and wherein the property of the sensor is a sensitivity of the sensor. 
     
     
         7 . The method of  claim 2 , further comprising compensating sensor data using the determined property of the sensor. 
     
     
         8 . The method of  claim 7 , wherein the compensating comprises correlating a predetermined relationship of the peak current to sensor sensitivity or change in sensor sensitivity and modifying a value or values of the sensor data responsive to the correlated sensor sensitivity or change in sensor sensitivity. 
     
     
         9 . The method of  claim 8 , wherein the predetermined relationship is a linear relationship over time of use of the analyte sensor. 
     
     
         10 . The method of  claim 8 , wherein the predetermined relationship is a non-linear relationship over time of use of the analyte sensor. 
     
     
         11 . The method  claim 8 , wherein the predetermined relationship is determined by prior testing of sensors similar to the analyte sensor. 
     
     
         12 . A system for determining a property of a continuous analyte sensor, the system comprising a sensor electronics configured to be operably connected to a continuous analyte sensor, the sensor electronics configured to:
 apply a bias voltage to an analyte sensor;   apply a voltage step above the bias voltage to the analyte sensor;   measure a signal response of the voltage step;   determine a peak current of the signal response; and   determine a property of the sensor by correlating the peak current to a predetermined relationship.   
     
     
         13 . The system of  claim 12 , wherein correlating the peak current to the predetermined relationship comprises calculating an impedance of the sensor based on the peak current and correlating the sensor impedance to the predetermined relationship. 
     
     
         14 . The system of  claim 12 , wherein the property of the sensor is a sensitivity of the sensor or a temperature of the sensor. 
     
     
         15 . The system of  claim 12 , wherein the peak current is a difference between a magnitude of the response prior to the voltage step and a magnitude of the largest measured response resulting from the voltage step. 
     
     
         16 . The system of  claim 12 , wherein the predetermined relationship is an impedance-to-sensor sensitivity relationship, and wherein the property of the sensor is a sensitivity of the sensor. 
     
     
         17 . The system of  claim 12 , wherein the sensor electronics are further configured to compensate sensor data using the determined property of the sensor. 
     
     
         18 . The system of  claim 17 , wherein the compensating comprises correlating a predetermined relationship of the peak current to sensor sensitivity or change in sensor sensitivity and modifying a value or values of the sensor data responsive to the correlated sensor sensitivity or change in sensor sensitivity. 
     
     
         19 . The system of  claim 18 , wherein the predetermined relationship is a linear relationship over time of use of the analyte sensor. 
     
     
         20 . The system of  claim 18 , wherein the predetermined relationship is a non-linear relationship over time of use of the analyte sensor. 
     
     
         21 . The system of  claim 18 , wherein the predetermined relationship is determined by prior testing of sensors similar to the analyte sensor. 
     
     
         22 . The system of  claim 12 , wherein the sensor electronics comprise a processor module, the processor module comprising instructions stored in computer memory, wherein the instructions, when executed by the processor module, cause the sensor electronics to apply the bias voltage to the analyte sensor, apply the voltage step above the bias voltage to the analyte sensor; measure the signal response of the voltage step, determine the peak current of the signal response, and determine the property of the sensor by correlating the peak current to the predetermined relationship.