US2014045928A1PendingUtilityA1
Polyphenol/theanine compositions
Est. expirySep 21, 2026(~0.2 yrs left)· nominal 20-yr term from priority
A61P 37/04A61P 31/12A61P 43/00A61P 31/00A61P 31/16A61P 37/00A61K 31/198A61K 31/353A61K 36/82A61P 11/00A61K 9/48
39
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Claims
Abstract
Disclosed herein are compositions comprising tea derived components which are useful in reducing the incidence of cold and/or flu in a subject. Specifically exemplified herein are compositions comprising predetermined amounts of L-theanine and EGCG, and methods of using same.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A method of reducing the incidence of colds and/or flu in a subject comprising orally administering a therapeutically effective amount of a composition comprising an admixture of an L-theanine composition comprising at least 10-100 percent L-theanine and a tea polyphenol composition comprising at least 10-100 percent EGCG, wherein said composition is administered according to a dosage amounting to at least 25 mg of L-theanine and at least 25 mg of EGCG per day.
2 . The method of claim 1 , wherein said composition is administered according to a dosage amounting to at least 100 mg of L-theanine per day.
3 . The method of claim 1 , wherein said composition is administered according to a dosage amounting to at least 150 mg L-theanine and at least 125 mg of EGCG per day.
4 . The method of claim 1 wherein said composition is administered according to a dosage amounting to between 150 to 600 mg of L-theanine and between 150 to 600 mg of EGCG per day.
5 . The method of claim 1 , wherein said composition comprises at least 200 mg of an admixture of an L-theanine composition and a tea polyphenol composition disposed in a capsule, wherein said L-theanine composition comprises at least 80 percent L-theanine and said decaffeinated tea polyphenol composition comprises at least 40 percent EGCG.
6 . The method of claim 5 , wherein said capsule comprises 300 mg of said admixture.
7 . The method of claim 5 , wherein said L-theanine composition comprises at least 90 percent L-theanine.
8 . The method of claim 5 , wherein said polyphenol composition comprises at least 45 percent EGCG.
9 . The method of claim 5 , wherein said composition is administered as two of said capsules per day.
10 . The method of claim 9 , wherein said capsules each contain at least 300 mg of said admixture.
11 . A method of reducing the severity of cold and/or flu symptoms in a subject experiencing cold and/or flu, said method comprising orally administering a therapeutically effective amount of a composition comprising an admixture of an L-theanine composition comprising 10-100 percent L-theanine and a tea polyphenol composition comprising 10-100 percent EGCG, wherein said composition is administered according to a dosage amounting to at least 25 mg of L-theanine and at least 25 mg of EGCG per day.
12 . The method of claim 11 , wherein said composition is administered according to a dosage amounting to at least 100 mg of L-theanine per day.
13 . The method of claim 11 , wherein said composition is administered according to a dosage amounting to at least 150 mg L-theanine and at least 125 mg of EGCG per day.
14 . The method of claim 11 wherein said composition is administered according to a dosage amounting to between 150 to 600 mg of L-theanine and between 150 to 600 mg of EGCG per day.
15 . The method of claim 11 , wherein said composition comprises at least 200 mg of an admixture of an L-theanine composition and a tea polyphenol composition disposed in a capsule, wherein said L-theanine composition comprises at least 80 percent L-theanine and said decaffeinated tea polyphenol composition comprises at least 40 percent EGCG.
16 . The method of claim 15 , wherein said capsule comprises 300 mg of said admixture.
17 . The method of claim 15 , wherein said L-theanine composition comprises at least 90 percent L-theanine.
18 . The method of claim 15 , wherein said polyphenol composition comprises at least 45 percent EGCG.
19 . The method of claim 15 , wherein said composition is administered as two of said capsules per day.
20 . The method of claim 19 , wherein said capsules each contain at least 300 mg of said admixture.
21 . A capsule or tablet comprising at least 50 mg of an admixture of an L-theanine composition comprising at least 10-100 percent L-theanine and a tea polyphenol composition comprising at least 10-100 percent EGCG.
22 . The capsule or table of claim 21 , wherein said capsule or tablet comprises at least 200 mg of an admixture of an L-theanine composition and a tea polyphenol composition, wherein said L-theanine composition comprises at least 80 percent L-theanine and said decaffeinated tea polyphenol composition comprises at least 40 percent EGCG.
23 . The capsule or tablet of claim 22 , wherein said capsule or tablet comprises 300 mg of said admixture.
24 . The capsule or tablet of claim 22 , wherein said L-theanine composition comprises at least 90 percent L-theanine or at least 95 percent L-theanine.
25 . The capsule or tablet of claim 22 , wherein said polyphenol composition comprises at least 45 percent EGCG or at least 50 percent EGCG.
26 . The capsule or tablet of claim 21 , wherein said capsule or tablet comprises at least 50 mg of L-theanine and at least 50 mg of EGCG.
26 . A composition comprising an admixture of an L-theanine composition and a decaffeinated tea polyphenol composition, wherein said L-theanine composition comprises 10-100 percent L-theanine and said tea polyphenol composition comprises 10-100 percent EGCG, wherein said L-theanine composition and tea polyphenol composition are present in a ratio of 2:1, 1.9:1, 1.8:1, 1.7:1, 1.6:1, 1.5:1, 1.4:1, 1.3:1, 1.2:1, 1:1, 1:1.1, 1:1.2, 1:1.3, 1:1.4, 1:1.5, 1:1.6, 1:1.7, 1:1.8, 1:1.9, 1:2, or 1:3 respective to each other.
27 . A method of enhancing immune function by γδ T cells in a subject comprising orally administering a therapeutically effective amount of a composition comprising L-theanine and EGCG, wherein said composition is administered according to a dosage amounting to at least 25 mg of L-theanine and at least 25 mg of EGCG per day.
28 . The method of claim 27 wherein said composition comprises an admixture of an L-theanine composition comprising at least 10-100 percent L-theanine and a tea polyphenol composition comprising at least 10-100 percent EGCG
29 . The method of claim 27 , wherein said composition is administered according to a dosage amounting to at least 100 mg of L-theanine per day.
30 . The method of claim 27 , wherein said composition is administered according to a dosage amounting to at least 150 mg L-theanine and at least 125 mg of EGCG per day.
31 . The method of claim 27 wherein said composition is administered according to a dosage amounting to between 150 to 600 mg of L-theanine and between 150 to 600 mg of EGCG per day.
32 . The method of claim 27 , wherein said composition comprises at least 50 mg of an admixture of an L-theanine composition and a decaffeinated tea polyphenol composition disposed in a capsule, wherein said L-theanine composition comprises at least 80 percent L-theanine and said tea polyphenol composition comprises at least 40 percent EGCG.
33 . The method of claim 1 , wherein said composition is administered orally in a beverage or food product.
34 . The method of claim 1 , wherein said composition comprises between 10 percent to 80 percent L-theanine, by weight, and between 10 percent to 80 percent EGCG, by weight.
35 . The method of claim 33 , wherein said composition comprises between 20 percent to 40 percent L-theanine, by weight, and between 20 percent to 40 percent EGCG, by weight.
36 . The composition of claim 26 , wherein said composition comprises between 10 percent to 80 percent L-theanine, by weight, and between 10 percent to 80 percent EGCG, by weight.
37 . The composition of claim 36 , wherein said composition comprises between 20 percent to 40 percent L-theanine, by weight, and between 20 percent to 40 percent EGCG, by weight.
37 . A method of reducing the incidence of cold and/or flu comprising orally administering the composition of claim 35 in therapeutically effective daily dosages over the course of at least 12 weeks, at least 18 weeks, 24, weeks, 30 weeks, 36, weeks, 42 weeks, 48 weeks, and 52 weeks.
38 . A method of reducing the length of cold and/or flu symptoms in a subject experiencing cold and/or flu, said method comprising orally administering a therapeutically effective amount of a composition comprising an admixture of an L-theanine composition comprising 10-100 percent L-theanine and a tea polyphenol composition comprising 10-100 percent EGCG, wherein said composition is administered according to a dosage amounting to at least 25 mg of L-theanine and at least 25 mg of EGCG per day.
39 . The method of claim 38 , wherein said composition is administered according to a dosage amounting to at least 125 mg of L-theanine and at least 125 mg of EGCG per day.
40 . An article of manufacture comprising between 25 ml to 5000 ml of a beverage comprising water, an amount of an EGCG composition, an amount of a L-theanine composition and a container in which the beverage is disposed, said article of manufacture comprising at least 25 mg of L-theanine and at least 25 mg of EGCG.
41 . The article of manufacture of claim 40 , wherein said EGCG composition comprises at least 40 percent EGCG composition and said L-theanine composition comprises at least 80 percent L-theanine.
42 . The article of manufacture of claim 40 , wherein the article of manufacture comprises at least 50 mg of L-theanine and at least 50 mg of EGCG.
43 . The article of manufacture of claim 40 , wherein said article of manufacture comprises at least 75 mg, 100 mg, 125 mg, 150 mg, 175 mg, 200 mg 225 mg or 250 mg of EGCG and at least 75 mg, 100 mg, 125 mg, 150 mg, 175 mg, 200 mg 225 mg or 250 mg mg of L-theanine.
44 . The article of manufacture of claim 40 , further comprising instructions to drink said beverage to reduce the incidence of colds and/or flu, or to boost immune function.
45 . A method of reducing incidence of cold and/or flu in a subject comprising providing the article of manufacture of claim 40 and instructing said subject to drink said beverage in said article of manufacture at a dosage of at least once daily.
46 . A method of boosting immune function in a subject comprising providing the article of manufacture of claim 40 and instructing said subject to drink said beverage in said article of manufacture at a dosage of at least once daily.
47 . An article of manufacture comprising at least 25 mg of a food product, an amount of an EGCG composition, an amount of a L-theanine composition and a container in which said food product is disposed, said article of manufacture comprising at least 25 mg of L-theanine and at least 25 mg of EGCG.
48 . A method of reducing incidence of cold and/or flu in a subject comprising providing the article of manufacture of claim 47 and instructing said subject to eat said food product in said article of manufacture at a dosage of at least once daily.
48 . A method of boosting immune function in a subject comprising providing the article of manufacture of claim 47 and instructing said subject to eat said food product in said article of manufacture at a dosage of at least once daily.
49 . A method of reducing the severity of cold and/or flu symptoms in a subject experiencing cold and/or flu, comprising providing the article of manufacture of claim 40 and instructing said subject to drink said beverage in said article of manufacture at a dosage of at least once daily.
50 . A method of reducing the severity of cold and/or flu symptoms in a subject experiencing cold and/or flu providing the article of manufacture of claim 47 and instructing said subject to eat said food product in said article of manufacture at a dosage of at least once daily.
51 . The method of claims 1 , 5 , 11 , 15 , 28 and 32 wherein said tea polyphenol composition is decaffeinated.
52 . The capsule of claims 21 and 22 wherein said tea polyphenol composition is decaffeinated.
53 . The composition of claim 26 , wherein said tea polyphenol composition is decaffeinated.Join the waitlist — get patent alerts
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