Environment and Method for Rapid Analysis of Genomic Sequence Data

Abstract

In one aspect, the present disclosure describes a method that may include receiving an indication of selection of a first diagnostic algorithm of two or more of diagnostic algorithms for analyzing genetic sequence data, where the indication is associated with an identifier. The method may further include retrieving, from a storage medium, first genetic sequencing data associated with the identifier and analyzing, by one or more processors, the first genetic sequencing data using the first diagnostic algorithm to obtain at least one diagnostic result.

What is claimed: 
     
         1 . A method comprising:
 receiving an indication of selection of a first diagnostic algorithm of a plurality of diagnostic algorithms for analyzing genetic sequence data, wherein the indication is associated with an identifier;   retrieving, from a storage medium, first genetic sequencing data associated with the identifier; and   analyzing, by one or more processors, the first genetic sequencing data using the first diagnostic algorithm to obtain at least one diagnostic result.   
     
     
         2 . The method of  claim 1 , wherein the one or more processors comprise a plurality of networked processors. 
     
     
         3 . The method of  claim 2 , wherein the plurality of networked processors are distributed in a cloud network environment in communication with a remote computing device, the method further comprising:
 providing the at least one diagnostic result to the remote computing device.   
     
     
         4 . The method of  claim 1 , wherein the first genetic sequencing data comprises genome data. 
     
     
         5 . The method of  claim 1 , wherein the first genetic sequencing data comprises transcriptome data. 
     
     
         6 . The method of  claim 1 , wherein the first genetic sequencing data comprises data derived from at least one of a human, animal, plant, viral, or bacterial biologic sample. 
     
     
         7 . The method of  claim 1 , wherein the at least one diagnostic result comprises at least one of (a) resistance patterns, (b) a respiratory panel, and (c) a transplantation panel. 
     
     
         8 . The method of  claim 1 , further comprising:
 determining a change in diagnosis practices relevant to the first diagnostic algorithm of the plurality of diagnostic algorithms; and   providing an alert associated with the identifier, wherein the alert comprises a recommendation for a new diagnostic algorithm of the plurality of diagnostic algorithms.   
     
     
         9 . The method of  claim 1 , wherein:
 each respective diagnostic algorithm of the plurality of diagnostic algorithms is associated with at least one category of a plurality of categories, and   the plurality of categories comprises one or more of virology, bacteriology, oncology, microbiology, and pathology.   
     
     
         10 . The method of  claim 9 , further comprising:
 generating, for presentation at a user device, interface information comprising a plurality of controls corresponding to the plurality of diagnostic algorithms, wherein
 each respective control of the plurality of controls is associated with a respective diagnostic algorithm of the plurality of diagnostic algorithms, 
 generating the interface information comprises associating each respective control of the plurality of controls with a respective visual indication corresponding to at least one category of the plurality of categories, and 
 receiving the indication of selection of the first diagnostic algorithm comprises receiving the indication of selection of a first control of the plurality of controls from the user device, wherein the first control corresponds to the first diagnostic algorithm. 
   
     
     
         11 . The method of  claim 10 , wherein associating each respective control of the plurality of controls with the respective visual indication comprises spatially organizing the plurality of controls into a plurality of groups, wherein each group of the plurality of groups corresponds to a respective category of the plurality of categories. 
     
     
         12 . The method of  claim 1 , wherein:
 the first diagnostic algorithm of the plurality of diagnostic algorithms is associated with at least one classification of a plurality of classifications, and   the plurality of classifications comprise one or more of research use, clinical study, certified, clinical diagnosis, and federal drug administration (FDA) approved.   
     
     
         13 . The method of  claim 12 , wherein:
 each respective diagnostic algorithm of the plurality of diagnostic algorithms is associated with a respective price, and   the price is based in part upon the respective classification of the plurality of classifications.   
     
     
         14 . The method of  claim 12 , further comprising:
 generating, for presentation at a user device, interface information comprising a plurality of controls corresponding to the plurality of diagnostic algorithms, wherein
 each respective control of the plurality of controls is associated with a respective diagnostic algorithm of the plurality of diagnostic algorithms, 
 generating the interface information comprises associating each respective control of the plurality of controls with a respective visual indication corresponding to at least one classification of the plurality of classifications, and 
 receiving the indication of selection of the first diagnostic algorithm comprises receiving the indication of selection of a first control of the plurality of controls from the user device, wherein the first control corresponds to the first diagnostic algorithm. 
   
     
     
         15 . The method of  claim 14 , wherein:
 associating each respective control of the plurality of controls with the respective visual indication comprises spatially organizing the plurality of controls into a plurality of groups, and   each group of the plurality of groups corresponds to a respective classification of the plurality of classifications.   
     
     
         16 . The method of  claim 1 , further comprising:
 generating report data comprising the at least one diagnostic result, wherein
 generating the report data comprises formatting the report data for review by a user. 
   
     
     
         17 . The method of  claim 16 , further comprising:
 retrieving, from a second storage medium, medical record data, wherein the report data comprises a portion of the medical record data.   
     
     
         18 . The method of  claim 16 , wherein:
 the identifier is associated with a set of meta data comprising demographic information; and   the report data comprises a portion of the demographic information.   
     
     
         19 . The method of  claim 1 , further comprising:
 determining, by the one or more processors, based upon the at least one diagnostic result, a second diagnostic algorithm of the plurality of diagnostic algorithms; and   providing, for review at a user device, an option for selecting analysis of second genetic sequencing data using the second diagnostic algorithm.   
     
     
         20 . The method of  claim 19 , further comprising:
 retrieving, from a second storage medium, medical record data, wherein
 determining the second diagnostic algorithm of the plurality of diagnostic algorithms comprises reviewing a portion of the medical record data. 
   
     
     
         21 . The method of  claim 19 , wherein determining the second diagnostic algorithm of the plurality of diagnostic algorithms comprises determining a popularity associated with the second diagnostic algorithm. 
     
     
         22 . The method of  claim 19 , wherein determining the second diagnostic algorithm of the plurality of diagnostic algorithms comprises determining a user rating associated with the second diagnostic algorithm. 
     
     
         23 . The method of  claim 19 , further comprising:
 receiving an indication of selection of the second diagnostic algorithm; and   responsive to the indication of selection, analyzing, by the one or more processors, the second genetic sequencing data using the second diagnostic algorithm to obtain at least one second diagnostic result.   
     
     
         24 . The method of  claim 23 , wherein the second genetic sequencing data comprises a different type than the first genetic sequencing data. 
     
     
         25 . The method of  claim 23 , wherein the second genetic sequencing data comprises the first genetic sequencing data. 
     
     
         26 . The method of  claim 23 , further comprising:
 generating report data, wherein
 the report data comprises the at least one diagnostic result and the at least one second diagnostic result, and 
 generating the report data comprises formatting the report data for review by a user. 
   
     
     
         27 . The method of  claim 1 , further comprising:
 prior to analyzing the first genetic sequence data, validating the first genetic sequence data.   
     
     
         28 . The method of  claim 27 , wherein validating the first genetic sequence data comprises comparing a type of the first genetic sequence data to a predetermined type of genetic sequence data for use with the first diagnostic algorithm. 
     
     
         29 . The method of  claim 28 , wherein the type comprises at least one of genome, transcriptome, DNA, and RNA. 
     
     
         30 . The method of  claim 29 , wherein validating the first genetic sequence data comprises determining a recency of the first genetic sequence data. 
     
     
         31 . A system comprising:
 a storage medium comprising first genetic sequence data;   one or more processors; and   memory storing instructions that, when executed, cause the processor to:
 receive an indication of selection of a first diagnostic algorithm of a plurality of diagnostic algorithms for analyzing genetic sequence data, wherein the indication is associated with an identifier; 
 retrieve, from the storage medium, the first genetic sequencing data, wherein the first genetic sequencing data is associated with the identifier; and 
 analyze, by the one or more processors, the first genetic sequencing data using the first diagnostic algorithm to obtain at least one diagnostic result. 
   
     
     
         32 . The system of  claim 31 , wherein the one or more processors comprise a plurality of networked processors. 
     
     
         33 . The system of  claim 32 , wherein the plurality of networked processors are distributed in a cloud network environment. 
     
     
         34 . The system of  claim 32 , wherein the instructions cause at least one of the plurality of networked processors to provide the at least one diagnostic result to a remote computing device. 
     
     
         35 . The system of  claim 31 , wherein the at least one diagnostic result comprises at least one of (a) resistance patterns, (b) a respiratory panel, and (c) a transplantation panel. 
     
     
         36 . The system of  claim 31 , wherein each respective diagnostic algorithm of the plurality of diagnostic algorithms is associated with at least one category of a plurality of categories, the plurality of categories comprising one or more of virology, bacteriology, oncology, microbiology, and pathology. 
     
     
         37 . A non-transitory computer readable medium, wherein the computer readable medium stores instructions that, when executed by a processor, cause the processor to:
 receive an indication of selection of a first diagnostic algorithm of a plurality of diagnostic algorithms for analyzing genetic sequence data, wherein the indication is associated with an identifier;   retrieve first genetic sequencing data associated with the identifier; and   analyze the first genetic sequencing data using the first diagnostic algorithm to obtain at least one diagnostic result.   
     
     
         38 . The computer readable medium of  claim 37 , wherein the processor comprises a plurality of networked processors. 
     
     
         39 . The computer readable medium of  claim 38 , wherein:
 the plurality of networked processors are distributed in a cloud network environment in communication with a remote computing device; and   the instructions cause at least one of the plurality of networked processors to provide the at least one diagnostic result to the remote computing device.