Device and method for management of aneurism, perforation and other vascular abnormalities

Abstract

This application is directed to a device comprising a covering attached to the device. A process of making a device with a specific covering attached is also disclosed. The application further discloses a method for the treatment of perforations, fistulas, ruptures, dehiscence and aneurisms in luminal vessels and organs of a subject.

1 - 15 . (canceled) 
     
     
         16 . A method for occluding an opening in a luminal vessel, comprising:
 placing at said opening a device comprising an expandable stent like body coated with a biodegradable material and an electrospun fibrous covering that covers said stent like body; and   expanding said stent like body to immobilize said device at said opening.   
     
     
         17 . The method of  claim 16 , wherein said luminal vessel is an artery or a vein. 
     
     
         18 . The method of  claim 16 , wherein said opening is an aneurysm, perforation, rupture or fistula. 
     
     
         19 . The method of  claim 18 , wherein the aneurysm is a berry aneurysm or a fusiform aneurysm. 
     
     
         20 . The method of  claim 18 , wherein the aneurysm is a cerebral, cardiac, pulmonary or aortic aneurysm. 
     
     
         21 . A method for treating condition in a luminal vessel in a subject, comprising:
 introducing into said subject a device comprising an expandable stent like body that is coated with a biodegradable material and covered with an electrospun covering;   positioning said device at a treatment site; and   expanding said expandable stent like body to immobilize said device at the treatment site.   
     
     
         22 . The method of  claim 21 , wherein said expandable stent like body comprises magnesium, iron or a polymer material. 
     
     
         23 . The method of  claim 21 , wherein said condition is a plaque in a blood vessel. 
     
     
         24 . The method of  claim 21 , wherein said condition is an acute myocardial infarction. 
     
     
         25 . The method of  claim 21 , wherein said condition is a hole or an opening in said luminal vessel. 
     
     
         26 . The method of  claim 21 , wherein said condition is a grafted vessel and wherein said device is emplaced under said graft to support the graft during the healing process and prevent leakage at the sutures. 
     
     
         27 . The method of  claim 16 , wherein said stent like body comprises a biodegradable or bioabsorbable material. 
     
     
         28 . The method of  claim 27 , wherein said biodegradable or bioabsorbable material comprises magnesium, iron or a polymer or co-polymer material. 
     
     
         29 . The method of  claim 16 , wherein said stent like body comprises a non-biodegradable or non-bioabsorbable material. 
     
     
         30 . The method of  claim 29 , wherein the non-biodegradable or non-bioabsorbable  material comprises stainless steel, cobalt chromium, or a non-degradable polymer. 
     
     
         31 . The method of  claim 16 , wherein the fibrous covering comprises a biodegradable or bioabsorbable material. 
     
     
         32 . The method of  claim 31 , wherein the biodegradable or bioabsorbable material comprises poly-(α-hydroxy acid) or poly-(L-lactic acid). 
     
     
         33 . The method of  claim 21 , wherein said stent like body comprises a biodegradable or bioabsorbable material. 
     
     
         34 . The method of  claim 33 , wherein said biodegradable or bioabsorbable material comprises magnesium, iron or a polymer or co-polymer material. 
     
     
         35 . The method of  claim 21 , wherein said stent like body comprises a non-biodegradable or non-bioabsorbable material. 
     
     
         36 . The method of  claim 35 , wherein the non-biodegradable or non-bioabsorbable material comprises stainless steel, cobalt chromium, or a non-degradable polymer. 
     
     
         37 . The method of  claim 21 , wherein the electrospun covering comprises a biodegradable or bioabsorbable material. 
     
     
         38 . The method of  claim 37 , wherein the biodegradable or bioabsorbable material comprises poly-(α-hydroxy acid) or poly-(L-lactic acid).