Antibody to a mutant g-csf for diagnosis of cancer

Abstract

Disclosed are a method, a composition, a microarray, an antibody and a kit for diagnosis and prognosis of cancer, based on detection of deletion of the exon 3 region of G-CSF gene or levels of a mutated G-CSF protein having a deletion of an amino acid sequence corresponding to the exon 3 region, wherein the deletion of the exon 3 region of the G-CSF gene is used as a cancer biomarker.

1 - 3 . (canceled) 
     
     
         4 . A diagnostic agent for cancer comprising the antibody according to  claim 10 . 
     
     
         5 . A diagnostic kit for cancer comprising the antibody according to  claim 10 . 
     
     
         6 . A microarray for diagnosis of cancer comprising the antibody according to  claim 10 . 
     
     
         7 - 9 . (canceled) 
     
     
         10 . An antibody specifically binding to the mutated G-CSF protein having a deletion of an amino acid sequence corresponding to an exon 3 region. 
     
     
         11 . The antibody as set forth in  claim 10 , wherein the antibody is a polyclonal antibody. 
     
     
         12 . The antibody as set forth in  claim 10 , wherein the antibody is a monoclonal antibody. 
     
     
         13 - 14 . (canceled)