US2014005147A1PendingUtilityA1
Dna polymerase inhibitors composition and methods
Est. expiryApr 26, 2027(~0.8 yrs left)· nominal 20-yr term from priority
Inventors:Carmela Vittorio
A61K 8/4953A61K 8/55A61K 31/7052A61K 31/675A61K 2800/782A61Q 9/04A61K 31/522
42
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Claims
Abstract
A topical composition containing a DNA polymerase inhibitor for removing hair as well as methods of inducing hair loss is described.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A pharmaceutical composition comprising 0.0001%-1% DNA polymerase inhibitor, wherein said pharmaceutical composition is a topical dermal pharmaceutical composition.
2 . The composition of claim 1 , wherein said composition is an ointment.
3 . The composition of claim 1 , wherein said composition is a lotion.
4 . The composition of claim 1 , wherein said composition is a cream.
5 . The composition of claim 1 , wherein said composition is a spray.
6 . The composition of claim 1 , wherein said composition is a gel.
7 . The composition of claim 1 , wherein said DNA polymerase inhibitor is a viral DNA polymerase inhibitor.
8 . The composition of claim 7 , wherein said viral DNA polymerase inhibitor is cidofovir, valacyclovir, famciclovir, acyclovir, penciclovir, trifluridine, vidarabine, ganciclovir, valaganciclovir, foscarnet, idoxuridine, lamivudine, or a mixture thereof.
9 . The composition of claim 7 , wherein said viral DNA polymerase inhibitor is cidofovir.
10 . A method of inducing hair loss in a subject, comprising the step of topically administering to said subject a composition comprising a DNA polymerase inhibitor, thereby inducing hair loss.
11 . The method of claim 10 , wherein said composition is an ointment.
12 . The method of claim 10 , wherein said composition is a lotion.
13 . The method of claim 10 , wherein said composition is a cream.
14 . The method of claim 10 , wherein said composition is a spray.
15 . The method of claim 10 , wherein said composition is a gel.
16 . The method of claim 10 , wherein said DNA polymerase inhibitor is a viral DNA polymerase inhibitor.
17 . The method of claim 16 , wherein said viral DNA polymerase inhibitor comprises cidofovir, valacyclovir, famciclovir, acyclovir, penciclovir, trifluridine, vidarabine, ganciclovir, valaganciclovir, foscarnet, idoxuridine, lamivudine, or a mixture thereof.
18 . The method of claim 17 , wherein said viral DNA polymerase inhibitor is cidofovir.
19 . The method of claim 10 , wherein said subject is human subject.
20 . A method of inhibiting hair growth in a subject, comprising the step of topically administering to said subject a composition comprising a DNA polymerase inhibitor, thereby inhibiting hair growth.
21 . The method of claim 20 , wherein said composition is an ointment.
22 . The method of claim 20 , wherein said composition is a lotion.
23 . The method of claim 20 , wherein said composition is a cream.
24 . The method of claim 20 , wherein said composition is a spray.
25 . The method of claim 20 , wherein said composition is a gel.
26 . The method of claim 20 , wherein said DNA polymerase inhibitor is a viral DNA polymerase inhibitor.
27 . The method of claim 26 , wherein said viral DNA polymerase inhibitor is cidofovir, valacyclovir, famciclovir, acyclovir, penciclovir, trifluridine, vidarabine, ganciclovir, valaganciclovir, foscarnet, idoxuridine, lamivudine, or a mixture thereof.
28 . The method of claim 27 , wherein said viral DNA polymerase inhibitor is cidofovir.
29 . The method of claim 20 , wherein said subject is human subject.
30 . A pharmaceutical composition comprising more than 0.0001% and less than 1% deoxycytidine analogue, said pharmaceutical composition is a topical dermal pharmaceutical composition.
31 . The composition of claim 30 , wherein said composition is an ointment.
32 . The composition of claim 30 , wherein said composition is a lotion.
33 . The composition of claim 30 , wherein said composition is a cream.
34 . The composition of claim 30 , wherein said composition is a spray.
35 . The composition of claim 30 , wherein said composition is a gel.
36 . The composition of claim 30 , wherein said deoxycytidine analogue is cidofovir, decitabin, gemcitabine, or a mixture thereof.
37 . A method of inducing hair loss in a subject, comprising the step of topically administering to said subject a composition comprising a deoxycytidine analogue, thereby inducing hair loss.
38 . The method of claim 37 , wherein said composition is an ointment.
39 . The method of claim 37 , wherein said composition is a lotion.
40 . The method of claim 37 , wherein said composition is a cream.
41 . The method of claim 37 , wherein said composition is a spray.
42 . The method of claim 37 , wherein said composition is a gel.
43 . The method of claim 37 , wherein said deoxycytidine analogue is cidofovir, decitabin, gemcitabine, or a mixture thereof.
44 . The method of claim 37 , wherein said subject is human subject.
45 . A method of inhibiting hair growth in a subject, comprising the step of topically administering to said subject a composition comprising a deoxycytidine analogue, thereby inhibiting hair growth.
46 . The method of claim 45 , wherein said composition is an ointment.
47 . The method of claim 45 , wherein said composition is a lotion.
48 . The method of claim 45 , wherein said composition is a cream.
49 . The method of claim 45 , wherein said composition is a spray.
50 . The method of claim 45 , wherein said composition is a gel.
51 . The method of claim 45 , wherein said deoxycytidine analogue is cidofovir, decitabin, gemcitabine, or a mixture thereof.
52 . The method of claim 45 , wherein said subject is human subject.Join the waitlist — get patent alerts
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