US2013345462A1PendingUtilityA1

Process for production of 4-oxoquinoline compound

54
Assignee: JAPAN TOBACCO INCPriority: Mar 6, 2006Filed: Jan 14, 2013Published: Dec 26, 2013
Est. expiryMar 6, 2026(expired)· nominal 20-yr term from priority
Inventors:Koji MatsudaKoji AndoShigeji OhkiTakahiro YamasakiJun-Ichi Hoshi
C07C 65/21C07C 229/34C07F 7/1804C07D 215/233C07D 215/56C07C 69/716C07C 229/30Y02P20/55
54
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, the present invention provides, for example, compounds represented by the formulas (6), (7-1), (7-2) and (8): wherein R is a fluorine atom or a methoxy group, R 1 is a C 1 -C 4 alkyl group, R 2 is a hydroxyl-protecting group, and X 2 is a halogen atom, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.

Claims

exact text as granted — not AI-modified
1 - 71 . (canceled) 
     
     
         72 . A compound of the following formula (7-1): 
       
         
           
           
               
               
           
         
         wherein R 1  is a C 1 -C 4  alkyl group, R 2  is a hydroxyl-protecting group, and X 2  is a halogen atom. 
       
     
     
         73 . A compound of the following formula (6): 
       
         
           
           
               
               
           
         
         wherein R is a fluorine atom or a methoxy group, R 1  is a C 1 -C 4  alkyl group, and X 2  is a halogen atom. 
       
     
     
         74 . A compound of the following formula (5): 
       
         
           
           
               
               
           
         
         wherein R is a fluorine atom or a methoxy group, R 1  is a C 1 -C 4  alkyl group, and X 2  is a halogen atom. 
       
     
     
         75 . A compound of the following formula (4): 
       
         
           
           
               
               
           
         
         wherein R is a fluorine atom or a methoxy group, R 1  is a C 1 -C 4  alkyl group, and X 2  is a halogen atom, 
       
       or a salt thereof. 
     
     
         76 . A compound of the following formula:

Join the waitlist — get patent alerts

Track US2013345462A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.