Functional foods comprising diamine oxidase and uses thereof

Abstract

The present invention relates to functional foods comprising DAO and their use for the prevention or treatment of diseases or pathological conditions associated with high levels of histamine in blood, in particular for the prevention or treatment of migraine, chronic fatigue, fibromyalgia, spondylitis and pain caused by muscle contractures.

1 . A functional food comprising DAO. 
     
     
         2 . A functional food comprising DAO, according to  claim 1 , wherein the DAO can be added to the food in free form, in the form of powder, lyophilized powder, microcapsules, nanocapsules or liposomes. 
     
     
         3 . A functional food according to  claim 1 , wherein the DAO is both of biotechnological origin and from plant or animal extraction. 
     
     
         4 . A functional food according to  claim 1 , wherein the DAO includes gastrointestinal protection. 
     
     
         5 . A functional food according to  claim 1 , wherein the food is a dairy-based product such as yogurt, milky beverages, a confectionery product, ice-cream or another beverage such as, for example, juice; a non-dairy-based product such as soya, oat, almond or rice milk; cereals and the like. 
     
     
         6 . A functional food according to  claim 1 , wherein the food is a nutritional or vitamin supplement. 
     
     
         7 . A functional food according to  claim 1 , wherein the DAO is present in a percentage comprised between 0.01 and 5% by weight of DAO as regards to the total weight of the food. 
     
     
         8 . A method of preventing or treating a disease or pathological condition associated with high histamine levels in blood, comprising administering a functional food comprising DAO. 
     
     
         9 . A method of preventing or treating migraine, comprising administering a functional food comprising DAO. 
     
     
         10 . A method of preventing or treating chronic fatigue, fibromyalgia, spondylitis and pain caused by muscular contractures, the method comprising administering a functional food comprising DAO. 
     
     
         11 . The method according to  claim 8 , wherein the DAO is present in a percentage comprised between 0.01% and 5% by weight of DAO as regards to the total weight of the food. 
     
     
         12 . The method according to  claim 9 , wherein the DAO is present in a percentage comprised between 0.01% and 5% by weight of DAO as regards to the total weight of the food. 
     
     
         13 . The method according to  claim 10 , wherein the DAO is present in a percentage comprised between 0.01% and 5% by weight of DAO as regards to the total weight of the food.