US2013337089A1PendingUtilityA1

Composition for preventing or treating hearing loss

45
Assignee: KANG TONG HOPriority: Mar 10, 2011Filed: Mar 8, 2012Published: Dec 19, 2013
Est. expiryMar 10, 2031(~4.6 yrs left)· nominal 20-yr term from priority
Inventors:Tong Ho KangBin Hong
A61K 9/2018A61K 36/804A61K 9/0019A61K 9/08A61K 9/145A61P 27/16A61K 36/43A23V 2002/00A61K 9/2059A23L 33/105A61K 36/39A61K 36/64A23L 1/3002A61K 36/185
45
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

Disclosed is a pharmaceutical composition for preventing or treating hearing loss, comprising Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy. In addition, the present invention provides a food composition for preventing or ameliorating hearing loss, comprising Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy. The composition inhibits hearing loss, in particular, acoustic trauma, temporary or permanent hearing loss by effectively inhibiting the threshold shift induced by noise and the likes, and thusit is effective in preventing or treating hearing loss. In addition, it can be administered orally, thereby drug compliance of patients can be enhanced.

Claims

exact text as granted — not AI-modified
1 . A pharmaceutical composition for preventing or treating hearing loss, comprising  Cuscuta japonica  Choisy extract, or the extract of  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and  Cuscuta japonica  Choisy. 
     
     
         2 . The pharmaceutical composition according to  claim 1 , wherein the hearing loss is noise-induced hearing loss. 
     
     
         3 . The pharmaceutical composition according to  claim 1 , wherein the extract of  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and  Cuscuta japonica  Choisy comprises 1:1.8 to 1:9 ratio of  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO to  Cuscuta japonica  Choisy. 
     
     
         4 . The pharmaceutical composition according to  claim 1 , wherein the extract is obtained by extract process comprising the extraction step of  Cuscuta japonica  Choisy, or  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and  Cuscuta japonica  Choisy with the extraction solvent selected from the group consisting of water, C 1 ˜C 4  alcohol, and the mixed solvent of water and C 1 ˜C 4  alcohol. 
     
     
         5 . The pharmaceutical composition according to  claim 1 , wherein the  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO is at least one selected from the group consisting of raw  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, dried  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and steamed  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, and the  Cuscuta japonica  Choisy is at least one selected from the group consisting of  Cuscuta chinensis  Lam.,  Cuscuta pentagona  Engelm.,  Cuscuta japonica  Choisy, and  Cuscuta australis  R. Br. 
     
     
         6 . A food composition for preventing or ameliorating hearing loss, comprising  Cuscuta japonica  Choisy extract, or the extract of  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and  Cuscuta japonica  Choisy. 
     
     
         7 . The food composition according to  claim 6 , wherein the hearing loss is noise-induced hearing loss. 
     
     
         8 . The food composition according to  claim 6 , wherein the extract of  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and  Cuscuta japonica  Choisy comprises 1:1.8 to 1:9 ratio of  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO to  Cuscuta japonica  Choisy. 
     
     
         9 . The food composition according to  claim 6 , wherein the extract is obtained by extract process comprising the extraction step of  Cuscuta japonica  Choisy, or  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and  Cuscuta japonica  Choisy with the extraction solvent selected from the group consisting of water, C 1 ˜C 4  alcohol, and the mixed solvent of water and C 1 ˜C 4  alcohol. 
     
     
         10 . The food composition according to  claim 6 , wherein the  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO is at least one selected from the group consisting of raw  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, dried  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and steamed  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, and the  Cuscuta japonica  Choisy is at least one selected from the group consisting of  Cuscuta chinensis  Lam.,  Cuscuta pentagona  Engelm.,  Cuscuta japonica  Choisy, and  Cuscuta australis  R. Br. 
     
     
         11 . The food composition according to  claim 7 , wherein the  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO is at least one selected from the group consisting of raw  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, dried  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and steamed  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, and the  Cuscuta japonica  Choisy is at least one selected from the group consisting of  Cuscuta chinensis  Lam.,  Cuscuta pentagona  Engelm.,  Cuscuta japonica  Choisy, and  Cuscuta australis  R. Br. 
     
     
         12 . The food composition according to  claim 8 , wherein the  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO is at least one selected from the group consisting of raw  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, dried  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and steamed  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, and the  Cuscuta japonica  Choisy is at least one selected from the group consisting of  Cuscuta chinensis  Lam.,  Cuscuta pentagona  Engelm.,  Cuscuta japonica  Choisy, and  Cuscuta australis  R. Br. 
     
     
         13 . The food composition according to  claim 9 , wherein the  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO is at least one selected from the group consisting of raw  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, dried  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and steamed  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, and the  Cuscuta japonica  Choisy is at least one selected from the group consisting of  Cuscuta chinensis  Lam.,  Cuscuta pentagona  Engelm.,  Cuscuta japonica  Choisy, and  Cuscuta australis  R. Br. 
     
     
         14 . The pharmaceutical composition according to  claim 2 , wherein the  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO is at least one selected from the group consisting of raw  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, dried  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and steamed  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, and the  Cuscuta japonica  Choisy is at least one selected from the group consisting of  Cuscuta chinensis  Lam.,  Cuscuta pentagona  Engelm.,  Cuscuta japonica  Choisy, and  Cuscuta australis  R. Br. 
     
     
         15 . The pharmaceutical composition according to  claim 3 , wherein the  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO is at least one selected from the group consisting of raw  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, dried  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and steamed  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, and the  Cuscuta japonica  Choisy is at least one selected from the group consisting of  Cuscuta chinensis  Lam.,  Cuscuta pentagona  Engelm.,  Cuscuta japonica  Choisy, and  Cuscuta australis  R. Br. 
     
     
         16 . The pharmaceutical composition according to  claim 4 , wherein the  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO is at least one selected from the group consisting of raw  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, dried  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO and steamed  Rehmannia glutinosa  Libschitz var.  purpurea  MAKINO, and the  Cuscuta japonica  Choisy is at least one selected from the group consisting of  Cuscuta chinensis  Lam.,  Cuscuta pentagona  Engelm.,  Cuscuta japonica  Choisy, and  Cuscuta australis  R. Br.

Join the waitlist — get patent alerts

Track US2013337089A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.