Cosmetic

Abstract

A composition is provided that includes a fish spawn protein isolate. A natural product extract is also present that includes unsaturated fatty acids and sterols. An emulsifier is provided to form a mixture of the isolate and the extract. A composition is also provided that includes an egg hatching protein isolate and at least one biocide protective of isolate activity. An emulsifier forms a mixture with the isolate that has an aqueous phase buffered to a pH of between 5.6 and 7.9. A process of producing such a cosmetic has an emulsion or an aqueous phase that is buffered to a pH of between 5.5 and 7.9 prior to the addition of isolate to the emulsion. A process of improving skin appearance is provided that includes the application of the cosmetic to the skin at least three times per week to achieve the improvement of the skin appearance.

1 . A cosmetic comprising:
 a fish spawn protein isolate having an anti-inflammatory effect on mammalian skin;   a natural product extract comprising unsaturated fatty acids and sterols, said natural product extract having anti-oxidant activity on the mammalian skin; and   an emulsifier or a solubilizer, or a combination thereof forming a mixture of said isolate and said extract.   
     
     
         2 . The cosmetic of  claim 1  wherein said fish spawn protein isolate is present from 0.00001 to 10 total weight percent. 
     
     
         3 . The cosmetic of  claim 1  wherein said natural product extract is a plant extract. 
     
     
         4 . The cosmetic of  claim 1  wherein said unsaturated fatty acids include at least one of an omega-3, omega-6, or omega-9 fatty acid. 
     
     
         5 . The cosmetic of  claim 1  wherein said sterols include at least one of cholesterol, campesterol, stigmasterol, or sitosterol. 
     
     
         6 . The cosmetic of  claim 1  further comprising an ascorbic acid or ascorbate salt. 
     
     
         7 . The cosmetic of  claim 1  wherein said fish spawn protein isolate, said natural product extract, and said emulsifier are all substantially free of silicone, petrolatum, synthetic paraben, and mineral oil. 
     
     
         8 . The cosmetic of  claim 1  wherein said fish spawn protein isolate comprises zonase. 
     
     
         9 . The cosmetic of  claim 1  wherein said fish spawn protein isolate consisting essentially of zonase as an active protein. 
     
     
         10 . The cosmetic of  claim 1  wherein said fish spawn protein isolate comprises leukolectin. 
     
     
         11 . The cosmetic of  claim 1  wherein said fish spawn protein isolate consisting essentially of leukolectins as active proteins. 
     
     
         12 . The cosmetic of  claim 1  wherein said fish spawn protein is derived from salmon roe. 
     
     
         13 . The cosmetic of  claim 1  wherein said fish spawn protein is derived from roe from at least one of whitefish, vendace, cod, capelin, and burbot. 
     
     
         14 . A cosmetic comprising:
 an egg hatching protein isolate having an anti-inflammatory effect on mammalian skin;   at least one biocide protective of activity of said egg hatching protein isolate for 3 months storage at 20° C. is provided while the activity when applied to subject skin after storage remains within 80% of unformulated and freshly isolated protein; and   an emulsifier or a solubilizer, or a combination thereof forming a mixture of said egg hatching protein isolate, said mixture having an aqueous phase, buffered to a pH of between 5.6 and 7.9.   
     
     
         15 . The cosmetic of  claim 14  wherein said egg hatching protein isolate, said at least one biocide, said emulsifier are all substantially free of silicone, petrolatum, synthetic paraben, and mineral oil. 
     
     
         16 . The cosmetic of  claim 14  wherein said at least one biocide comprises Japanese honeysuckle extract in combination with another plant extract to inhibit organisms found on a healthy human subject, said organisms being Gram positive bacteria, Gram negative bacteria, and fungi. 
     
     
         17 . The cosmetic of  claim 14  wherein said egg hatching protein isolate is present from 0.00001 to 1 total weight percent. 
     
     
         18 . The cosmetic of  claim 14  further comprising a natural product extract including unsaturated fatty acids and sterols, said extract having anti-oxidant activity on the mammalian skin. 
     
     
         19 . The cosmetic of  claim 18  wherein said extract is derived from a red algae, brown algae or a tuft-forming cyanobacteria. 
     
     
         20 . The cosmetic of  claim 14  further comprising an ascorbic acid or ascorbate salt. 
     
     
         21 . The cosmetic of  claim 14  wherein said egg hatching protein isolate, said at least one biocide, and said emulsifier are all substantially free of silicone, petrolatum, synthetic paraben, and mineral oil. 
     
     
         22 . The cosmetic of  claim 14  wherein said egg hatching protein isolate comprises zonase. 
     
     
         23 . The cosmetic of  claim 14  wherein said egg hatching protein isolate consisting essentially of zonase as an active protein. 
     
     
         24 . The cosmetic of  claim 14  wherein said egg hatching protein isolate comprises leukolectin. 
     
     
         25 . The cosmetic of  claim 14  wherein said egg hatching protein isolate consisting essentially of leukolectins as active proteins. 
     
     
         26 . The cosmetic of  claim 14  wherein said egg hatching protein isolate is derived from fish roe. 
     
     
         27 . A process for producing a cosmetic of  claim 14  comprising:
 forming at least one aqueous phase and at least one hydrophobic phase, said emulsifier and said at least one biocide present in at least one of said at least one aqueous phase and said at least one hydrophobic phase; 
 combining said at least one aqueous phase and said at least one hydrophobic phase to form an emulsion; buffering said emulsion or said at least one aqueous phase to a pH of between 5.5 and 7.9; and 
 then adding said egg hatching protein isolate to said emulsion. 
 
     
     
         28 . The process of  claim 27  further comprising adding a natural product extract to said emulsion, said natural product extract comprising unsaturated fatty acids and sterols, said natural product extract having anti-oxidant activity on the mammalian skin. 
     
     
         29 . The process of  claim 27  wherein said adding occurs independent of heating and high sheer mixing. 
     
     
         30 . A process of improving skin appearance comprising:
 applying to skin of a mammal a composition of  claim 1  at a level of from 1×10 −6  to 0.1 mg of said fish spawn protein isolate and 2×10 −7  to 0.02 mg of said unsaturated fatty acids per square cm of skin at least three times per week to achieve the skin rejuvenation.