US2013331768A1PendingUtilityA1

Eye treatment

37
Individually held — no corporate assignee on recordPriority: Dec 29, 2010Filed: Dec 28, 2011Published: Dec 12, 2013
Est. expiryDec 29, 2030(~4.4 yrs left)· nominal 20-yr term from priority
Inventors:Louis D. Nichamin
A61P 33/14A61P 27/04A61K 36/82A61P 29/00A61F 9/0008A61K 9/0048A61F 9/00A61P 27/02A61P 31/04A61M 2037/0007A61K 36/61
37
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Claims

Abstract

Methods and kits for treating or preventing an eye condition or for cleaning an eye area tissue are provided. A method of the invention includes administering an isoprenoidal essential oil to eye area tissue, chafing eye area tissue with an abrasive, and removing the abrasive. A kit according to the invention includes an isoprenoidal essential oil, an abrasive for chafing eye area tissue, and in instruction for use for treating an eye condition or cleansing an eye area tissue. The invention also includes a composition of matter comprising an isoprenoidal essential oil and a plurality of abrasive particles in ophthamologically acceptable base.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of treating or preventing an eye condition in eye area tissue comprising:
 administering an isoprenoidal essential oil to eye area tissue;   chafing eye area tissue with an abrasive; and   removing the abrasive.   
     
     
         2 . The method of  claim 1  wherein treating an eye condition comprises treating a condition selected from the group consisting of: anterior blepharitis, posterior blepharitis,  Demodex  induced blepharitis, conjunctivitis, dry eye, meibomitis, ocular  Demodex  infestation, and ocular rosacea. 
     
     
         3 . The method of  claim 1  wherein administering an isoprenoidal essential oil to eye area tissue comprises administering tea tree oil. 
     
     
         4 . The method of  claim 3  wherein the concentration of tea tree oil is about 0.5% (w/w) to about 4% (w/w). 
     
     
         5 . The method of  claim 3  about the concentration of tea tree oil is about 5% (w/w) to about 50% (w/w). 
     
     
         6 . The method of  claim 1  wherein chafing eye area tissue comprises chafing a tissue selected from the group consisting of: upper eyelid tissue, lower eyelid tissue, eyelid margin tissue, anterior eyelid margin tissue, posterior eyelid margin tissue, and eyelash follicle. 
     
     
         7 . The method of  claim 1  wherein chafing eye area tissue with an abrasive comprises chafing with abrasive particles having a size from about 1 μm to about 600 μm in a longest dimension. 
     
     
         8 . The method of  claim 7  wherein chafing eye area tissue comprises chafing with abrasive particles having a size from about 25 μm to less than 300 μm in a longest dimension. 
     
     
         9 . The method of  claim 7  wherein chafing eye area tissue comprises chafing with abrasive particles having a size from 300 μm to about 600 μm in a longest dimension. 
     
     
         10 . The method of  claim 1  wherein chafing the eye area comprises performing a motion selected from the group consisting of rubbing and vibrating. 
     
     
         11 . The method of  claim 1  wherein administering an isoprenoidal essential oil further comprises administering an abrasive at the same time. 
     
     
         12 . The method of  claim 1  wherein the abrasive comprises abrasive particles and removing the abrasive comprises removing the abrasive particles using a material selected from the group consisting of a moving gas at a pressure less than atmospheric pressure and an aqueous solution. 
     
     
         13 . A kit for treating an eye condition or cleansing an eye area tissue, the kit comprising:
 an isoprenoidal essential oil for application to eye tissue;   an abrasive for chafing eye area tissue; and   an instruction for use for treating an eye condition or cleansing an eye area tissue.   
     
     
         14 . The kit of  claim 13  wherein the abrasive comprises abrasive particles. 
     
     
         15 . The kit of  claim 14  wherein the abrasive particles comprises particles having a size from about 25 μm to less than 300 μm in a longest dimension. 
     
     
         16 . The kit of  claim 14  wherein the abrasive particles comprises particles having a size from about 25 μm to less than 300 μm in a longest dimension. 
     
     
         17 . The kit of  claim 14  wherein the abrasive particles comprises particles having a size from 300 μm to about 600 μm in a longest dimension. 
     
     
         18 . The kit of  claim 14  wherein the isoprenoidal essential oil and the abrasive particles form a mixture. 
     
     
         19 . The kit of  claim 13  wherein the isoprenoidal essential oil comprises tea tree oil at a concentration of between about 0.5% (w/w) and about 50% (w/w). 
     
     
         20 . The kit of  claim 19  wherein the concentration of the tea tree oil is between about 5% and about 50%. 
     
     
         21 . The kit of  claim 20  wherein the concentration of the tea tree oil is between about 0.5% to about 4%. 
     
     
         22 . The kit of  claim 13  further comprising an applicator for applying the isoprenoidal essential oil to an eye tissue wherein the applicator comprises the abrasive. 
     
     
         23 . A composition of matter comprising:
 about 0.5% to about 4% isoprenoidal essential oil in an ophthalmologically acceptable base; and   a plurality of abrasive particles.   
     
     
         24 . The composition of  claim 23  wherein the isoprenoidal essential oil comprises tea tree oil.

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