Circadian rhythm regulatory agent

Abstract

A circadian rhythm regulatory agent having as an active ingredient an alkylresorcinol represented by general formula (I) below and a circadian rhythm regulatory agent containing as an active ingredient an alkylresorcinol-containing extract from a cereal or a nut containing an alkylresorcinol of the following general formula (I). In the following general formula (I), R 1 is a saturated or unsaturated alkyl group; and R 2 is hydrogen or methyl. In general formula (I), R 1 is preferably at the para-position with respect to R 2 , and R 1 is preferably a saturated or unsaturated alkyl group having 15 to 27 carbon atoms.

1 . A circadian rhythm regulatory agent comprising as an active ingredient an alkylresorcinol represented by general formula (1): 
       
         
           
           
               
               
           
         
         wherein R 1  represents a saturated or unsaturated alkyl group; and R 2  represents a hydrogen atom or a methyl group. 
       
     
     
         2 . The circadian rhythm regulatory agent according to  claim 1 , wherein R 1  in general formula (I) is at the para-position with respect to R 2 . 
     
     
         3 . The circadian rhythm regulatory agent according to  claim 1 , wherein R 1  in general formula (I) is a saturated or unsaturated alkyl group having 15 to 27 carbon atoms. 
     
     
         4 . The circadian rhythm regulatory agent according to  claim 1 , wherein, in general formula (I), R 1  is a saturated or unsaturated alkyl group having 15 to 25 carbon atoms, and R 2  is a hydrogen atom. 
     
     
         5 . The circadian rhythm regulatory agent according to  claim 1 , wherein the active ingredient is an extract which comprises an alkylresorcinol and is prepared from a cereal or a nut. 
     
     
         6 . The circadian rhythm regulatory agent according to  claim 5 , wherein the alkylresorcinol-containing extract is a cereal extract obtained by extracting a cereal with an alcohol. 
     
     
         7 . The circadian rhythm regulatory agent according to  claim 5 , wherein the cereal is wheat or rye, and the nut is a cashew nut. 
     
     
         8 . The circadian rhythm regulatory agent according to  claim 2 , wherein R 1  in general formula (I) is a saturated or unsaturated alkyl group having 15 to 27 carbon atoms. 
     
     
         9 . The circadian rhythm regulatory agent according to  claim 2 , wherein, in general formula (I), R 1  is a saturated or unsaturated alkyl group having 15 to 25 carbon atoms, and R 2  is a hydrogen atom. 
     
     
         10 . The circadian rhythm regulatory agent according to  claim 2 , wherein the active ingredient is an extract which comprises an alkylresorcinol and is prepared from a cereal or a nut. 
     
     
         11 . The circadian rhythm regulatory agent according to  claim 3 , wherein the active ingredient is an extract which comprises an alkylresorcinol and is prepared from a cereal or a nut. 
     
     
         12 . The circadian rhythm regulatory agent according to  claim 4 , wherein the active ingredient is an extract which comprises an alkylresorcinol and is prepared from a cereal or a nut. 
     
     
         13 . The circadian rhythm regulatory agent according to  claim 6 , wherein the cereal is wheat or rye, and the nut is a cashew nut. 
     
     
         14 . The circadian rhythm regulatory agent according to  claim 8 , wherein the active ingredient is an extract which comprises an alkylresorcinol and is prepared from a cereal or a nut. 
     
     
         15 . The circadian rhythm regulatory agent according to  claim 9 , wherein the active ingredient is an extract which comprises an alkylresorcinol and is prepared from a cereal or a nut. 
     
     
         16 . The circadian rhythm regulatory agent according to  claim 10 , wherein the cereal is wheat or rye, and the nut is a cashew nut. 
     
     
         17 . The circadian rhythm regulatory agent according to  claim 11 , wherein the cereal is wheat or rye, and the nut is a cashew nut. 
     
     
         18 . The circadian rhythm regulatory agent according to  claim 12 , wherein the cereal is wheat or rye, and the nut is a cashew nut.