Treatment of Psychiatric Conditions

Abstract

The number of acne lesions in a human subject is reduced by administering to the subject a pharmaceutical composition that includes a pharmaceutically acceptable carrier and a therapeutically effective amount of an agent that selectively binds IL-1α. Anxiety and other psychiatric conditions are also improved with this treatment.

What is claimed is: 
     
         1 - 6 . (canceled) 
     
     
         7 . A method of reducing anxiety in a human subject, the method comprising the step of administering to the subject a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an amount of an agent that selectively binds IL-1α effective to reduce anxiety in the subject. 
     
     
         8 . The method of  claim 7 , wherein the agent is an anti-IL-1α antibody. 
     
     
         9 . The method of  claim 8 , wherein the anti-IL-1α antibody is a monoclonal antibody. 
     
     
         10 . The method of  claim 8 , wherein the monoclonal antibody is an IgG1. 
     
     
         11 . The method of  claim 8 , wherein the monoclonal antibody comprises a complementarity determining region of MABp1. 
     
     
         12 . The method of  claim 8 , wherein the monoclonal antibody is MABp1. 
     
     
         13 . The method of  claim 7 , wherein the subject has acne.