US2013281470A1PendingUtilityA1

Use of (R)-Penciclovir Triphosphate for the Manufacture of a Medicament for the Treatment of Viral Diseases

Assignee: VERE HODGE RICHARD ANTHONYPriority: Apr 24, 1995Filed: Jun 19, 2013Published: Oct 24, 2013

Est. expiryApr 24, 2015(expired)· nominal 20-yr term from priority

Inventors:Richard Anthony Vere Hodge Raymond F. Schinazi

A61P 37/04A61P 31/00A61K 31/522A61K 31/661A61P 31/12A61P 31/18

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Claims

Abstract

A method of treatment of: i) HIV-1 infections in mammals, including humans; or ii) HBV infections in mammals, including humans; which method comprises the administration to the human in need of such treatment, an effective amount of the (R)-enantiomer of the triphosphate of a compound of formula (A) or a pharmaceutically acceptable salt thereof; and compounds for use in the method.

Claims

exact text as granted — not AI-modified

1 . A method of treatment of:
 i) HIV-1 infections in mammals, including humans; or   ii) HBV infections in mammals, including humans;   
       which method comprises the administration to the human in need of such treatment, an effective amount of the (R)-enantiomer of the triphosphate of a compound of formula (A); 
       
         
           
           
               
               
           
         
       
       ((R)-PCV-TP), or a pharmaceutically acceptable salt thereof; 
     
     
         2 . A method, composition or use according to  claim 1  wherein the (R)-PCV-TP is in the form of a bioprecursor which is a derivative of (R)-PCV-MP which liberates intracellularly (R)-PCV-MP which is in turn converted to (R)-PCV-TP.

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