US2013261071A1PendingUtilityA1

Exopolysaccharide

Assignee: PROCTER & GAMBLEPriority: May 4, 2007Filed: Jan 10, 2013Published: Oct 3, 2013
Est. expiryMay 4, 2027(~0.8 yrs left)· nominal 20-yr term from priority
A61P 37/00A61P 37/02A61P 29/00C07H 5/06A61P 1/10A61P 1/12A61P 1/00A61P 19/02A61P 1/04A61P 1/06C08B 37/006A23L 33/135C08B 37/00C12P 19/04A61K 31/715A23L 1/3014
38
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Claims

Abstract

An isolated polysaccharide has the structure [-β(1,3)-D-GaIpNAc-β(1,4)-D-Glcp-] n . The polysaccharide may be from a Bifidobacterium strain NCIMB 41003. The polysaccharide exhibits immunomodulatory activity.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . An isolated polysaccharide comprising the structure [-β(1,3)-D-GalpNAc-β(1,4)-D-Glcp-] n . 
     
     
         2 . An isolated polysaccharide from a bacterial strain comprising the structure [-β(1,3)-D-GaIpNAc-β(1,4)-D-Glcp-] n . 
     
     
         3 . An isolated polysaccharide from a  Bifidobacterium  strain comprising the structure [-β(1,3)-D-GaIpNAc-β(1,4)-D-Glcp-] n . 
     
     
         4 . An isolated polysaccharide from a  Bifidobacterium  strain comprising the structure [-β(1,3)-D-GaIpNAc-β(1,4)-D-Glcp-] n . 
     
     
         5 . An isolated polysaccharide from  Bifidobacterium  strain NCIMB  41003  comprising the structure [-β(1,3)-D-GaIpNAc-β(1,4)-D-Glcp-] n . 
     
     
         6 . Use of a polysaccharide according to any of  claims 1  to  5  in the preparation of a medicament for treating or preventing undesirable inflammatory activity. 
     
     
         7 . Use of a polysaccharide according to any of  claims 1  to  5  in the preparation of a medicament for treating or preventing undesirable gastrointestinal inflammatory activity. 
     
     
         8 . Use according to  claim 7  wherein the gastrointestinal inflammatory activity is Crohn's disease, ulcerative colitis, irritable bowel syndrome, pouchitis, post infection colitis,  Clostridium difficile  associated diarrhoea, Rotavirus associated diarrhoea or post infective diarrhoea. 
     
     
         9 . Use of a polysaccharide according to any of  claims 1  to  5  in the preparation of a medicament for treating or preventing rheumatoid arthritis. 
     
     
         10 . Use of a polysaccharide according to any of  claims 1  to  5  in the preparation of a medicament for treating or preventing autoimmune disorders. 
     
     
         11 . A pharmaceutical composition comprising a polysaccharide according to  claims 1  to  5  and a pharmaceutically acceptable carrier. 
     
     
         12 . A foodstuff comprising a polysaccharide according to any of  claims 1  to  5 . 
     
     
         13 . A foodstuff as claimed in  claim 12  wherein the foodstuff is one or more selected from the group comprising: yogurts, cereals, beverages. 
     
     
         14 . An isolated polysaccharide substantially as hereinbefore described. 
     
     
         15 . Use of an isolated polysaccharide substantially as hereinbefore described. 
     
     
         16 . A pharmaceutical composition substantially as hereinbefore described. 
     
     
         17 . A foodstuff substantially as hereinbefore described. 
     
     
         18 . An isolated polysaccharide from a  Bifidobacterium  strain comprising the structure [-β(1,3)-D-GalpNAc-β(1,4)-D-Glcp-] n . 
     
     
         19 . The use of a polysaccharide as claimed in  claim 18  in the preparation of a medicament for treating or preventing autoimmune disorders.

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