US2013253218A1PendingUtilityA1

Process for preparing prostaglandin derivatives

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Assignee: YONSUNG FINE CHEMICAL CO LTDPriority: Mar 11, 2009Filed: May 23, 2013Published: Sep 26, 2013
Est. expiryMar 11, 2029(~2.6 yrs left)· nominal 20-yr term from priority
Inventors:Changyoung OhKee Young LeeYong Hyun KimJae-Eun Joo
C07C 2601/08Y02P20/55C07C 69/618C07C 67/317C07C 405/00C07C 69/608C07C 233/11C07C 69/734C07C 69/587
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Claims

Abstract

The present invention relates to a process for preparing a prostaglandin derivative and an intermediate therefor. In accordance with the present invention, the prostaglandin F (PGF) derivative can be efficiently prepared with high purity by removing the protecting group of a protected prostaglandin E (PGE) derivative obtained from conjugate addition and then stereoselectively reducing the ketone group on the cyclopentanone ring of the PGE derivative.

Claims

exact text as granted — not AI-modified
1 . Travoprost having a purity of 99.5% or more. 
     
     
         2 . Bimatoprost having a purity of 99.5% or more. 
     
     
         3 . A compound of the following formula (8): 
       
         
           
           
               
               
           
         
       
     
     
         4 . A compound of the following formula (9):

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