Treatment of infection

Abstract

The invention relates to compositions including a substance useful as an adjuvant for potentiating an immune response, and methods of using the composition in individuals with infections of tissue within or adjacent to a transformation zone, such as the transformation zone of the cervix or anal canal.

1 . (canceled) 
     
     
         2 . (canceled) 
     
     
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         9 . A method for treating an infection in an individual including the steps of selecting an individual having an infection of tissue within or adjacent to a transformation zone; and contacting the tissue with a therapeutically effective amount of a composition including a substance useful as an adjuvant for potentiating an immune response and which is a combination of aluminium hydroxide and 3-deacylated monophospholipid A. 
     
     
         10 . The method of  claim 9  wherein the infection is a HPV infection. 
     
     
         11 . A method of minimising the incidence of a complication of a cervical or anal HPV infection in an individual including the step of selecting an individual having a cervical or anal HPV infection and contacting infected tissue in or adjacent to a transformation zone in the individual with a therapeutically effected amount of a composition including a substance useful as an adjuvant for potentiating an immune response and which is a combination of aluminium hydroxide and 3-deacylated monophospholipid A. 
     
     
         12 . (canceled) 
     
     
         13 . The method of  claim 9 , wherein the transformation zone is the cervical or the anal transformation zone. 
     
     
         14 . (canceled) 
     
     
         15 . A method for treating an individual having a cervical or anal HPV infection including the step of contacting infected tissue within or adjacent to the cervical or anal transformation zone in the individual with a therapeutically effective amount of a composition including a substance useful as an adjuvant for potentiating an immune response and which is a combination of aluminium hydroxide and 3-deacylated monophospholipid A. 
     
     
         16 . (canceled) 
     
     
         17 . The method of  claim 9 , wherein the transformation zone is abraded or ruptured prior to contacting the infected tissue within or adjacent to the transformation zone. 
     
     
         18 . (canceled) 
     
     
         19 . The method of  claim 9 , wherein the composition is brought into contact with the surface of the infected tissue by direct application to the surface or injection of the composition into cells at the surface of the infected tissue. 
     
     
         20 . (canceled) 
     
     
         21 . (canceled) 
     
     
         22 . The method of  claim 11 , wherein the transformation zone is abraded or ruptured prior to contacting the infected tissue within or adjacent to the transformation zone. 
     
     
         23 . The method of  claim 15 , wherein the transformation zone is abraded or ruptured prior to contacting the infected tissue within or adjacent to the transformation zone. 
     
     
         24 . The method of  claim 11 , wherein the composition is brought into contact with the surface of the infected tissue by direct application to the surface or injection of the composition into cells at the surface of the infected tissue. 
     
     
         25 . The method of  claim 15 , wherein the composition is brought into contact with the surface of the infected tissue by direct application to the surface or injection of the composition into cells at the surface of the infected tissue.