US2013244984A1PendingUtilityA1

Ceramide Production Promoter

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Assignee: KAO CORPPriority: Jul 31, 2008Filed: Apr 25, 2013Published: Sep 19, 2013
Est. expiryJul 31, 2028(~2 yrs left)· nominal 20-yr term from priority
Inventors:Yoshiya SugaiHiroshi HashimotoShinya AmanoShotaro ItoYoshie ShimotoyodomeYoriko Nakagiri
A61Q 19/007A61P 17/16A61K 8/55A61Q 19/00A61K 31/661A61K 8/553
59
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Claims

Abstract

Provided are a drug, a cosmetic, etc. for promoting production of ceramide. Provided is a ceramide production promoter including a compound represented by the formula (1) or salts thereof as an active ingredient (in the formula, R 1 represents a phosphono group or a hydrogen atom, R 2 represents an alkyl group having 8 to 24 carbon atoms or an acyl group having 8 to 24 carbon atoms, and R 3 represents an alkyl group having 1 to 24 carbon atoms when R 1 represents a phosphono group or represents a phosphono group when R 1 represents a hydrogen atom, or a salt thereof as an active ingredient.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 .- 6 . (canceled) 
     
     
         7 . A method of moisturizing skin, comprising administering a compound represented by the following formula (1): 
       
         
           
           
               
               
           
         
         wherein R 1  represents a phosphono group or a hydrogen atom, R 2  represents an alkyl group having 8 to 24 carbon atoms or an acyl group having 8 to 24 carbon atoms, and R 3  represents an alkyl group having 1 to 24 carbon atoms when R 1  represents a phosphono group or represents a phosphono group when R 1  represents a hydrogen atom, or a salt thereof as an active ingredient, to a subject who wants to moisturize his or her skin. 
       
     
     
         8 . The method of  claim 7 , wherein said R 1  is said hydrogen group. 
     
     
         9 . The method of  claim 8 , wherein said R 2  is said alkyl group. 
     
     
         10 . The method of  claim 8 , wherein said R 2  is said acyl group. 
     
     
         11 . The method of  claim 7 , wherein said R 1  is said phosphono group. 
     
     
         12 . The method of  claim 11 , wherein said R 2  is said alkyl group. 
     
     
         13 . The method of  claim 11 , wherein said R 2  is said acyl group. 
     
     
         14 . The method according to  claim 11 , wherein R 3  represents an alkyl group having 1 to 6 carbon atoms. 
     
     
         15 . The method of  claim 7 , wherein said administering is by applying said compound externally to the skin. 
     
     
         16 . The method of  claim 13 , wherein said compound is applied to said skin in a cosmetic composition.

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