US2013217783A1PendingUtilityA1
Therapeutic Compounds
Est. expiryMay 9, 2027(~0.8 yrs left)· nominal 20-yr term from priority
Inventors:Thomas E. Jenkins
A61P 37/00A61P 39/00A61P 39/06A61P 43/00A61P 9/10A61P 35/00A61P 27/02A61P 25/30A61P 29/00A61P 25/20A61P 25/22A61P 25/28A61P 25/08A61P 25/16A61P 27/12A61P 25/14A61P 25/06A61P 25/00A61P 11/00A61P 1/08A61P 21/02A61P 1/04A61P 17/02A61P 23/00C07C 245/20C07C 39/06C07B 2200/07C07C 37/055C07C 39/27C07C 37/003C07C 37/045C07C 271/44C07C 37/86A61K 9/0019A61K 31/055
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Claims
Abstract
A (−)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, is useful as an anesthetic.
Claims
exact text as granted — not AI-modified1 - 19 . (canceled)
20 . A method for treating nausea or vomiting in an animal comprising administering to the animal an effective amount of a (−)-stereoisomer of formula (I):
wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof.
21 . The method of claim 20 , wherein X is H.
22 . The method of claim 20 , which is a pharmaceutically acceptable salt thereof.
23 . The method of claim 22 , wherein X is H.
24 . The method of claim 20 , wherein the method comprises intravenous administration.
25 . The method of claim 24 , wherein X is H.
26 . The method of claim 20 , wherein the (−)-stereoisomer of formula (I) is formulated as a lipid emulsion.
27 . A method for preventing nausea or vomiting in an animal comprising administering to the animal an effective amount of a (−)-stereoisomer of formula (I):
wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof.
28 . The method of claim 27 , wherein X is H.
29 . The method of claim 27 , which is a pharmaceutically acceptable salt thereof.
30 . The method of claim 29 , wherein X is H.
31 . The method of claim 27 , wherein the method comprises intravenous administration.
32 . The method of claim 31 , wherein X is H.
33 . The method of claim 27 , wherein the (−)-stereoisomer of formula (I) is formulated as a lipid emulsion.
34 . A method for promoting an antiemetic effect in an animal comprising administering to the animal an effective amount of a (−)-stereoisomer of formula (I):
wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof.
35 . The method of claim 34 , wherein X is H.
36 . The method of claim 34 , which is a pharmaceutically acceptable salt thereof.
37 . The method of claim 36 , wherein X is H.
38 . The method of claim 34 , wherein the method comprises intravenous administration.
39 . The method of claim 38 , wherein X is H.
40 . The method of claim 34 , wherein the (−)-stereoisomer of formula (I) is formulated as a lipid emulsion.Join the waitlist — get patent alerts
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