US2013210722A1PendingUtilityA1

Methods for using peptide agonists having glp-1 activity

Assignee: ZEALAND PHARMA ASPriority: Jul 12, 1999Filed: Mar 26, 2013Published: Aug 15, 2013
Est. expiryJul 12, 2019(expired)· nominal 20-yr term from priority
A61P 3/10A61P 3/04C07K 14/605A61K 47/62A61K 38/00A61K 38/26C07K 14/57563
61
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Claims

Abstract

Novel peptide agonists of GLP-1 activity useful for lowering blood glucose levels. The novel peptides comprise variants of the GLP-1 or the exendin-4 polypeptide sequence and are pharmacologically active and stable. These peptides are useful in the treatment of diseases that benefit from regulation of excess levels of blood glucose and/or regulation of gastric emptying, such as diabetes and eating disorders.

Claims

exact text as granted — not AI-modified
1 . A method for treating type 2 diabetes mellitus in a subject in need thereof, said method comprising administering to said subject desPro 36 -exendin-4(1-39)-Lys 6 -NH 2  (SEQ ID NO: 93), or a pharmaceutically acceptable salt thereof in an amount that is effective for the treatment of type 2 diabetes mellitus.

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