Protective wound dressing device for oral and pharyngeal space

Abstract

The present invention provides a wound dressing comprising a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof and a 1,1-disubstituted ethylene monomer. The present invention further provides methods of using the wound dressing and kits containing the wound dressing.

1 - 5 . (canceled) 
     
     
         6 . A method of treating a wound comprising:
 (1) applying a 1,1-disubstituted monomer to a wound and embedding a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof in said 1,1-disubstituted ethylene monome;   (2) polymerizing the 1,1-disubstituted ethylene monomer; and   (3) dissolving said water-soluble molding matrix leaving a molded polymer applied to said wound.   
     
     
         7 . The method of  claim 6  wherein said 1,1-disubstituted ethylene monomer comprises a cyanoacrylate. 
     
     
         8 . The method of  claim 7  wherein said cyanoacrylate is selected from the group consisting of ethyl cyanoacrylate, n-butyl cyanoacrylate, 2-octyl cyanoacrylate, methoxyethyl cyanoacrylate, ethoxyethyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, 1-methoxy-2-propyl cyanoacrylate, hexyl cyanoacrylate, butyl lactoyl cyanoacrylate, butyl glycolcyl cyanoacrylate, ethyl lactoyl cyanoacrylate, and ethyl glycoloyl cyanoacrylate. method of  claim 6  wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 5 mm in any given dimension. 
     
     
         10 . The wound dressing of  claim 6  wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 3 mm in any given dimension. 
     
     
         11 - 15 . (canceled) 
     
     
         16 . A method of treating a wound comprising:
 (1) applying a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and mixtures thereof to a wound and applying a 1,1-disubstituted ethylene monomer to the wound filling at least a portion of at least one cell of the water-soluble molding matrix;   (2) polymerizing the 1,1-disubstituted ethylene monomer; and   (3) dissolving said water-soluble molding matrix leaving a molded polymer applied to said wound.   
     
     
         17 . The method of  claim 16  wherein said 1,1-disubstituted ethylene monomer comprises a cyanoacrylate. 
     
     
         18 . The method of  claim 17  wherein said cyanoacrylate is selected from the group consisting of ethyl cyanoacrylate, n-butyl cyanoacrylate, 2-octyl cyanoacrylate, methoxyethyl cyanoacrylate, ethoxyethyl cyanoacrylate, dodecyl cyanoacrylate, 2-ethylhexyl cyanoacrylate, butyl cyanoacrylate, 3-methoxybutyl cyanoacrylate, 2-butoxyethyl cyanoacrylate, 2-isopropoxyethyl cyanoacrylate, 1-methoxy-2-propyl cyanoacrylate, hexyl cyanoacrylate, butyl lactoyl cyanoacrylate, butyl glycolcyl cyanoacrylate, ethyl lactoyl cyanoacrylate, and ethyl glycoloyl cyanoacrylate. 
     
     
         19 . The method of  claim 16  wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 5 mm in any given dimension. 
     
     
         20 . The wound dressing of  claim 16  wherein the tessellated water-soluble molding matrix is comprised of cells measuring less than about 3 mm in any given dimension.