Personal care and medicinal products incorporating orgnosulfur groups

Abstract

Personal care products useful for the maintenance of personal appearance and good health and minor treatments that do not require professional health care, as well as products that provide a combination of anti-microbial, anti-oxidant, anti-inflammatory, and anti-aging properties and are suitable for use without a prescription. The products utilize a biomembrane permeable organosulfur compound that can redox cycle between thiol, disulfide, and thiosulfinate forms in response to oxidants and antioxidants inside and outside of cells. Example products include an anti-microbial toothpaste with anti-plaque properties, an anti-inflammatory skin lotion with antioxidant, antimicrobial, and deodorant properties, and an anti-toxin skin lotion with anti-arsenicosis properties.

1 - 19 . (canceled) 
     
     
         20 . An anti-plaque oral care dentifrice composition comprising a membrane permeable  allium  related compound selected from the group consisting of allyl mercaptan, n-propyl mercaptan, diallyl disulfide, di-n-propyl disulfide. n-propyl allyl disulfide and combinations thereof, mixed with an orally acceptable carrier suitable for application to the teeth. 
     
     
         22 . The composition of claim  1  where said membrane permeable  allium  related compound is allyl mercaptan. 
     
     
         23 . The composition of claim  1  where said membrane permeable  allium  related compound is diallyl disulfide. 
     
     
         24 . The composition of  claim 23  where said diallyl disulfide is the diallyl disulfide of garlic oil. 
     
     
         25 . The composition of claim  1  where said membrane permeable  allium  related compound is di-n-propyl disulfide. 
     
     
         26 . The composition of  claim 25  where said di-n-propyl disulfide is the di-n-propyl disulfide of onion oil. 
     
     
         27 . A method of making an anti-plaque oral care dentifrice composition comprising mixing a membrane permeable  allium  related compound selected from the group consisting of allyl mercaptan, n-propyl mercaptan, diallyl disulfide, di-n-propyl disulfide. n-propyl allyl disulfide and combinations thereof, with an orally acceptable carrier suitable for application to the teeth. 
     
     
         28 . The method of  claim 27  where said membrane permeable  allium  related compound is allyl mercaptan. 
     
     
         29 . The method of  claim 27  where said membrane permeable  allium  related compound is di-n-propyl disulfide. 
     
     
         30 . A method of treating the accumulation of dental plaque consisting of brushing the teeth with an effective amount of a membrane permeable  allium  related compound selected from the group consisting of allyl mercaptan, n-propyl mercaptan, diallyl disulfide, di-n-propyl disulfide. n-propyl allyl disulfide and combinations thereof, mixed with an orally acceptable carrier suitable for application to the teeth. 
     
     
         31 . The method of  claim 30  where said membrane permeable  allium  related compound is allyl mercaptan. 
     
     
         32 . The method of  claim 30  where said membrane permeable  allium  related compound is diallyl disulfide. 
     
     
         33 . The method of  claim 30  where said membrane permeable  allium  related compound is di-n-propyl disulfide.