US2013102783A1PendingUtilityA1

Substituted diketopiperazines and their use as oxytocin antagonists

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Assignee: GLAXO GROUP LTDPriority: Jun 4, 2003Filed: Dec 14, 2012Published: Apr 25, 2013
Est. expiryJun 4, 2023(expired)· nominal 20-yr term from priority
Inventors:John Liddle
A61P 5/36A61P 3/04A61P 9/04A61P 9/12A61P 5/12A61P 5/10A61P 43/00A61P 25/28A61P 15/06A61P 15/00A61P 1/16A61K 31/5377C07D 241/08C07D 413/06A61K 9/0053C07D 413/14
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Claims

Abstract

Compounds of formula (1) wherein R 1 is 2-indanyl, R 2 is 1-methylpropyl, R 3 is 2-methyl-1,3-oxazol-4-yl and R 4 and R 5 together with the nitrogen atom to which they are attached represents morpholino, process for their preparation, pharmaceutical compositions containing them and their use in medicine.

Claims

exact text as granted — not AI-modified
1 . A compound which is {(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-6-[(1R)-1-methylpropyl]-2,5-dioxo-1-piperazinyl}(2-methyl-1,3-oxazol-4-yl)acetic acid.

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