US2013039992A1PendingUtilityA1

Honey-Based Gel Composition

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Assignee: COMVITA NEW ZEALAND LTDPriority: Apr 7, 2010Filed: Apr 7, 2011Published: Feb 14, 2013
Est. expiryApr 7, 2030(~3.7 yrs left)· nominal 20-yr term from priority
Inventors:Fatma Bilge Thompson
A61P 17/02A61K 31/7028A61K 31/23A61K 9/0014A61K 35/644A61K 9/06A61L 26/0057
26
PatentIndex Score
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Cited by
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References
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Claims

Abstract

A honey based composition is described. The composition includes a mixture of honey, a short chain fatty alcohol and a fatty ester or wax. The composition has applications for use in wound dressings and in one embodiment may be a gel. The composition has a higher than expected storage stability, remaining stable for many weeks when held at elevated temperatures and retains all of the other desirable characteristics including anti-microbial activity.

Claims

exact text as granted — not AI-modified
1 . A composition for treating a patient wherein the composition comprises:
 a. at least 50% wt honey or a honey derivative:   b. 2-15% wt of a naturally derived short chain fatty alcohol with non-ionic surfactant properties;   c. 1 to 50% wt of a topical carrier or vehicle selected from a naturally derived fatty ester, a wax and wax-like compounds or mixtures thereof having a set point of 45° C. or less,   
       wherein the composition has been subjected to a sterilisation effective dosage of radiation and is storage stable for a time period of at least 24 hours at 40° C. 
     
     
         2 . The composition as claimed in  claim 1  wherein the composition is stable for at least 8 days when stored at 40° C. 
     
     
         3 . The composition as claimed in  claim 1  wherein the composition is stable for at least 21 days when stored at 30° C. 
     
     
         4 . The composition as claimed in  claim 1  wherein the composition is stable for at least 15 weeks when stored at 30° C. 
     
     
         5 . The composition as claimed in  claim 1  wherein the composition is a gel. 
     
     
         6 . The composition as claimed in  claim 1  wherein the composition has a viscosity of 50×10 3  to 600×10 3  cPs at 25° C. 
     
     
         7 . The composition as claimed in  claim 1  wherein the topical carrier or vehicle is selected from the group consisting of: a fatty ester, synthetic wax, beeswax, vegetal wax, mineral wax, a spermaceti wax constituent, carnauba wax and jojoba liquid wax. 
     
     
         8 . The composition as claimed in  claim 1  wherein the topical carrier or vehicle is myristyl myristate. 
     
     
         9 . The composition as claimed in  claim 1  wherein the topical carrier or vehicle has a melting point of about 37° C. or greater. 
     
     
         10 . The composition as claimed in  claim 1  wherein the honey has both peroxide and non-peroxide activity. 
     
     
         11 . The composition as claimed in  claim 1  wherein the honey constitutes approximately 70-90% wt of the composition. 
     
     
         12 . The composition as claimed in  claim 1  wherein the naturally derived short chain fatty alcohol is selected from fatty alcohols with a tail comprising 6 to 10 carbon atoms. 
     
     
         13 . The composition as claimed in  claim 1  wherein the naturally derived short chain fatty alcohol is selected from the group consisting of: caprylyl capryl glucoside, coco glucoside, lauryl glucoside, cetearyl olivate, sorbitan olivate, polyglyceryl-6 caprylate, polyglyceryl-5 laurate, polyglyceryl-10 laurate, polyglyceryl-5 oleate, polyglyceryl-5 dioleate, polyglyceryl-10 diisostearate, polyglyceryl-3 stearate, polyglyceryl-3 palmitate, polyglyceryl-3 polyricinoleate, glyceryl oleate, sodium stearoyl lactylate, glyceryl stearate citrate, and combinations thereof. 
     
     
         14 . The composition as claimed in  claim 1  wherein the naturally derived short chain fatty alcohol comprises from about 2% to about 10% wt of the composition. 
     
     
         15 . The composition as claimed in  claim 1  wherein the naturally derived short chain fatty alcohol comprises from about 2% to about 7% wt of the composition. 
     
     
         16 . The composition as claimed in  claim 1  wherein the naturally derived short chain fatty alcohol comprises from about 5% wt of the composition. 
     
     
         17 . The composition as claimed in  claim 1  wherein the topical carrier or vehicle comprises from about 10% to about 30% wt of the composition. 
     
     
         18 . The composition as claimed in  claim 1  wherein the topical carrier or vehicle comprises about 15% wt of the composition. 
     
     
         19 . The composition as claimed in  claim 1  wherein the pH remains between 3.0 and 60 for the duration of storage. 
     
     
         20 . The composition as claimed in  claim 1  wherein the pH remains between 4.0 and 5.0 for the duration of storage. 
     
     
         21 . A gelatinous composition consisting of:
 a. 70-90% wt honey   b. 2-15% wt myristyl myristate   c. 2-10% wt caprylyl capryl glucoside.   
     
     
         22 . The composition as claimed in  claim 21  wherein the composition is irradiated with a sterilisation effective dose of radiation. 
     
     
         23 . The composition as claimed in  claim 21  wherein the composition has a viscosity of 50×10 3  to 600×10 cPs at 25° C. 
     
     
         24 . The composition as claimed in  claim 21  wherein the composition is stable for at least 8 days when stored at 40° C. 
     
     
         25 . The composition as claimed in  claim 21  wherein the composition is stable for at least 21 days when stored at 30° C. 
     
     
         26 . The composition as claimed in  claim 21  wherein the composition is stable for at least 15 weeks when stored at 30° C.

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