Diagnostic for cancer

Abstract

An agent for diagnosing cancer comprising, as an active ingredient, a compound represented by the following formula (I) (R 1 represents hydrogen atom, or a substituent; R 2 to R 7 represent hydrogen atom, hydroxyl group, an alkyl group, or a halogen atom; R 8 and R 9 represent hydrogen atom, or an alkyl group; and X represents a C 1 -C 3 alkylene group), which specifically emits fluorescence in a cancerous tissue within a short time when applied to a part in which presence of a cancerous tissue is suspected.

1 . An agent for diagnosing cancer comprising a compound represented by the following formula (I): 
       
         
           
           
               
               
           
         
         wherein R 1  represents a hydrogen atom, or the same or different one to four substituents binding to the benzene ring; R 2 , R 3 , R 4 , R 5 , R 6 , and R 7  independently represent a hydrogen atom, a hydroxyl group, an alkyl group, or a halogen atom; R 8  and R 9  independently represent a hydrogen atom, or an alkyl group; and X represents a C 1 -C 3  alkylene group,
 or a salt thereof as an active ingredient. 
 
       
     
     
         2 . The agent for diagnosing cancer according to  claim 1 , wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , and R 9  are hydrogen atoms, and X is a methylene group. 
     
     
         3 . The agent for diagnosing cancer according to  claim 1 , which is used for a surgical treatment of a cancer or a diagnosis for a cancer. 
     
     
         4 . The agent for diagnosing cancer according to  claim 3 , wherein the surgical treatment of a cancer or the diagnosis for a cancer is an open surgery, an endoscopic surgery, or endoscopy. 
     
     
         5 . The agent for diagnosing cancer according to  claim 4 , which is used for quick diagnosis during surgery.