US2013017183A1PendingUtilityA1

Compositions containing non-polar compounds

49
Individually held — no corporate assignee on recordPriority: Jun 23, 2008Filed: Sep 14, 2012Published: Jan 17, 2013
Est. expiryJun 23, 2028(~1.9 yrs left)· nominal 20-yr term from priority
Inventors:Philip J. Bromley
A61P 35/00A61P 9/00A61P 39/06A23L 33/11A61P 25/00A61P 29/00A23L 33/12
49
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Claims

Abstract

Provided herein are compositions and methods for preparing foods and beverages that contain additives. Additives include nutraceuticals, pharmaceuticals, and supplements, such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids, conjugated fatty acids, and other fatty acids; phytochemicals, including phytosterols; other oils; and coenzymes, including Coenzyme Q10, and other oil-based additives.

Claims

exact text as granted — not AI-modified
1 . A liquid nanoemulsion concentrate, comprising:
 polysorbate or a polyoxyethylene sorbitan monooleate (polysorbate 80) analog in an amount between about 17% and about 26%, inclusive, by weight, of the concentrate;   water in an amount between about 60% and about 79%, inclusive, by weight, of the concentrate;   a non-polar ingredient that is selected from among any one or more of polyunsaturated fatty acids, Coenzyme Q10 compounds, and phytosterols in an amount between about 5% and about 10%, inclusive, by weight, of the concentrate.   
     
     
         2 . The liquid nanoemulsion concentrate of  claim 1 , wherein the non-polar ingredient is one or more of a Coenzyme Q10 compound, and a phytosterol. 
     
     
         3 . The liquid nanoemulsion concentrate of  claim 1 , wherein the amount of water is between about 65% and about 76%, or between about 68% and about 76%, by weight, of the concentrate. 
     
     
         4 . The liquid nanoemulsion concentrate of  claim 1 , wherein the polysorbate 80 analog is a polysorbate 80 homolog. 
     
     
         5 . The liquid nanoemulsion concentrate of  claim 4 , wherein the polysorbate 80 homolog differs from polysorbate 80 by one or more methylene unit(s). 
     
     
         6 . The liquid nanoemulsion concentrate of  claim 4 , wherein the polysorbate 80 analog is polysorbate 60, polysorbate 40, or polysorbate 20. 
     
     
         7 . The liquid nanoemulsion concentrate of  claim 1 , wherein the amount of polysorbate or a polysorbate 80 analog is between about 18% and about 26%. 
     
     
         8 . The liquid nanoemulsion concentrate of  claim 1 , wherein the non-polar ingredient contains at least one polyunsaturated fatty acid. 
     
     
         9 . The liquid nanoemulsion concentrate of  claim 1 , wherein the non-polar ingredient contains a Coenzyme Q10 compound and the Coenzyme Q10 compound is ubidecarenone. 
     
     
         10 . The liquid nanoemulsion concentrate of  claim 1 , further comprising a co-surfactant in an amount sufficient to stabilize the concentrate. 
     
     
         11 . The liquid nanoemulsion concentrate of  claim 10 , wherein the co-surfactant contains a phospholipid. 
     
     
         12 . The liquid nanoemulsion concentrate of  claim 11 , wherein the phospholipid comprises phosphatidylcholine. 
     
     
         13 . The liquid nanoemulsion concentrate of  claim 1 , further comprising a preservative, in amount sufficient to preserve the concentrate. 
     
     
         14 . The liquid nanoemulsion concentrate of  claim 13 , wherein preservative contains benzyl alcohol. 
     
     
         15 . The liquid nanoemulsion concentrate of  claim 1 , further comprising a solvent that dissolves the non-polar ingredient and differs therefrom, wherein the amount of solvent is sufficient to dissolve the non-polar ingredient. 
     
     
         16 . The liquid nanoemulsion concentrate of  claim 15 , wherein the solvent contains a Vitamin E oil, a flaxseed oil, or a combination thereof. 
     
     
         17 . The liquid nanoemulsion concentrate of  claim 1 , comprising from about 0.1% to less than 1% of an emulsion stabilizer. 
     
     
         18 . The liquid nanoemulsion concentrate of  claim 1 , further comprising one or more flavors in an amount sufficient to enhance the taste of the concentrate, the smell of the concentrate, or a combination thereof. 
     
     
         19 . The liquid nanoemulsion concentrate of  claim 18 , wherein the one or more flavors contains lemon oil, D-limonene, or a combination thereof. 
     
     
         20 . A method for preparing a liquid nanoemulsion concentrate of  claim 1 , comprising:
 (a) generating an oil phase by:
 (i) mixing one or more first oil phase ingredients in a first vessel and heating the first oil phase ingredients at least until the first oil phase ingredients dissolve, 
 (ii) adding one or more additional oil phase ingredients to the first vessel, and 
 (iii) mixing and heating the first and the additional oil phase ingredients, 
   wherein the oil phase ingredients comprise polysorbate or a polysorbate 80 analog in an amount between about 16% and about 30%, by weight, of the concentrate, and a non-polar ingredient, in an amount between about 5% and about 10%, by weight, of the concentrate;   (b) generating a water phase by:
 (i) mixing one or more water phase ingredients in a second vessel, and 
 (ii) heating the one or more water phase ingredients; and 
   (c) emulsifying the oil phase and the water phase, thereby generating a liquid nanoemulsion concentrate.   
     
     
         21 . The method of  claim 20 , wherein the polysorbate 80 analog is a polysorbate 80 homolog. 
     
     
         22 . The method of  claim 21 , wherein the polysorbate 80 homolog differs from polysorbate 80 by one or more methylene unit(s). 
     
     
         23 . The method of  claim 21 , wherein the polysorbate 80 analog is polysorbate 60, polysorbate 40 or polysorbate 20. 
     
     
         24 . The method of  claim 20 , wherein the non-polar ingredient is selected from among any one or more of polyunsaturated fatty acids, coenzyme Q10 compounds and phytosterols. 
     
     
         25 . The method of  claim 20 , wherein the non-polar ingredient contains a coenzyme. 
     
     
         26 . The method of  claim 20 , wherein the non-polar ingredient contains a Coenzyme Q10 compound and the Coenzyme Q10 compound is ubidecarenone. 
     
     
         27 . The method of  claim 20 , wherein the water phase ingredients contain water and the water is added at an amount between 60% or about 60% and 80% or about 80%, by weight, of the concentrate. 
     
     
         28 . The method of  claim 27 , the water is added at an amount between about 60% and about 79%; or between about 65% and about 76%; or between about 68% and about 76%, by weight, of the concentrate. 
     
     
         29 . The method of  claim 20 , wherein the polysorbate or polysorbate 80 analog is added at an amount is between about 17% and about 26%; or between about 18% and about 26%; or between about 20% and about 26%; or between about 16% and about 18%; or about 20%; or about 21%; or about 22%; or about 23%; or about 24%; or about 25%, by weight, of the concentrate. 
     
     
         30 . A method for preparing a powder, comprising spray drying or freeze drying the liquid nanoemulsion concentrate of  claim 1 . 
     
     
         31 . A method of providing a non-polar ingredient in a beverage, comprising:
 adding a liquid nanoemulsion concentrate of  claim 1  to an aqueous medium in an amount, whereby:   the aqueous medium contains an effective amount of the non-polar ingredient; and   the beverage containing the concentrate is as clear as in the absence of the non-polar ingredient.   
     
     
         32 . The method of  claim 31 , wherein the beverage is water, soda, milk, juice or a sports or nutrition beverage. 
     
     
         33 . The method of  claim 31 , wherein the non-polar ingredient is selected from among any one or more of polyunsaturated fatty acids, Coenzyme Q10 compounds, and phytosterols. 
     
     
         34 . A liquid nanoemulsion concentrate, comprising:
 polysorbate or a polyoxyethylene sorbitan monooleate (polysorbate 80) analog in an amount of about 21%; or about 22%; or about 23%; or about 24%; or about 25%, by weight, up to about 30%, by weight, of the concentrate;   water in an amount between about 60% and about 79%, inclusive, by weight, of the concentrate; and   a non-polar ingredient that is selected from among any one or more of polyunsaturated fatty acids, Coenzyme Q10 compounds, and phytosterols in an amount between about 5% and about 10%, inclusive, by weight, of the concentrate.   
     
     
         35 . The liquid nanoemulsion concentrate of  claim 1 , wherein the amount of polysorbate or a polysorbate 80 analog is between 20% and about 26%, by weight, of the concentrate. 
     
     
         36 . A liquid nanoemulsion concentrate, comprising:
 polysorbate or a polyoxyethylene sorbitan monooleate (polysorbate 80) analog in an amount between about 16% and about 30%, inclusive, by weight, of the concentrate;   water in an amount between about 60% and about 79%, inclusive, by weight, of the concentrate; and   a non-polar ingredient that is selected from among any one or more of polyunsaturated fatty acids, Coenzyme Q10 compounds, and phytosterols in an amount between about 5% and about 10%, inclusive, by weight, of the concentrate.   
     
     
         37 . The liquid nanoemulsion concentrate of  claim 1 , wherein the polysorbate is polysorbate 80. 
     
     
         38 . The liquid nanoemulsion concentrate of  claim 34 , wherein the polysorbate is polysorbate 80. 
     
     
         39 . The liquid nanoemulsion concentrate of  claim 36 , wherein the polysorbate is polysorbate 80.

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