Gas conditioning

Abstract

A compound for the manufacturing of a medicament for reducing or preventing mesothelial cell damage includes a mixture of a carrier gas and between 1 volume percent and 29 volume percent of nitrous oxide gas (N 2 O) and can be used for prevention of adhesion formation, pain reduction, reducing or preventing acute inflammation, reducing or preventing CO 2 resorbtion or reducing tumor cell implantation upon surgery.

1 - 31 . (canceled) 
     
     
         32 . Use of a mixture of a carrier gas and nitrous oxide gas, the nitrous oxide gas being between 1 volume percent and 29 volume percent, for the manufacture of a medicament for reducing or preventing mesothelial cell damage. 
     
     
         33 . Use according to  claim 32  for reducing or preventing mesothelial cell damage during surgery in a cavity by flowing the medicament in or over the cavity. 
     
     
         34 . Use according to  claim 32  for reducing or preventing mesothelial cell damage by or during pneumoperitoneum or for flow over a body during open surgery. 
     
     
         35 . Use according to  claim 32 , wherein the mixture comprises between 5 and 20 volume percentage nitrous oxide gas. 
     
     
         36 . Use according to  claim 32 , wherein the mixture furthermore comprises between 1 and 10 volume percentage of oxygen gas. 
     
     
         37 . Use according to  claim 32  for reducing or preventing adhesion formation. 
     
     
         38 . Use according to  claim 32  for reducing or preventing pain. 
     
     
         39 . Use according to  claim 32  for reducing or preventing acute inflammation. 
     
     
         40 . Use according to  claim 32  for reducing or preventing CO 2  resorbtion. 
     
     
         41 . Use according to  claim 32  for tumor implantation reduction. 
     
     
         42 . Use according to  claim 32 , wherein the carrier gas is carbon dioxide gas and/or wherein the solubility of the carrier gas is larger than 0.5 g/l in water. 
     
     
         43 . A conditioning system for use in surgery, comprising a gas supply system comprising a gas supplying means arranged to provide a mixture of gas in or over a cavity wherein surgery is performed, the gas supply system providing a mixture of gas for use in surgery, wherein the gas supply system supplies gas mixtures comprising a carrier gas and between 1 volume percent and 29 volume percent nitrous oxide gas (N 2 O). 
     
     
         44 . A conditioning system according to  claim 43 , the gas supplying means comprising an endoscopic insufflation means supplying the gas mixture as pneumoperitoneum. 
     
     
         45 . A conditioning system according to  claim 43 , wherein the gas supplying means comprises a gas location means comprising upstanding walls that maintain the gas mixture at the cavity wherein surgery is performed and/or wherein the gas supplying means is arranged to supply gas mixtures comprising between 5 and 20 volume percentage nitrous oxide gas and/or wherein the gas supplying means is arranged to provide between 1 and 10 volume percentage oxygen gas and/or wherein the gas supplying means comprises a mixing unit that mixes individual gasses from individual gas supplies and/or wherein the gas supplying means comprises an aspiration device that removes gases from a living creature and/or from a surgical area. 
     
     
         46 . A conditioning system according to  claim 43 , wherein the carrier gas is carbon dioxide. 
     
     
         47 . A conditioning system according to  claim 43 , wherein the gas supplying means comprises a moistener that moistens the gas mixture and/or wherein the conditioning system comprises a sprinkler that directly moistens the cavity. 
     
     
         48 . A conditioning system according  claim 43 , wherein the gas supplying means comprises a heating and/or cooling device that controls the temperature of the gas mixture. 
     
     
         49 . A conditioning system according to  claim 43 , wherein the gas supplying means comprises a controller programmed to supply the gas mixture and/or wherein the gas supplying means comprises a controller programmed to initially provide a gas or gas mixture comprising the carrier gas but no nitrous oxide gas and to increase the nitrous oxide gas concentration thereafter to supply the gas mixture, and/or wherein the gas supplying means comprises a controller programmed to control a ratio nitrous oxide gas to carrier gas in the mixture, and/or wherein the gas supplying means comprises a controller programmed to control the ratio nitrous oxide gas to carrier gas in the mixture according to a predetermined dynamic ratio, and/or wherein the gas supplying means comprises a controller programmed to provide between 1 and 10 volume percentage oxygen gas, and/or wherein the gas supplying means comprises a controller programmed to control the temperature of the gas mixture and/or humidity of the cavity. 
     
     
         50 . A conditioning system according to  claim 43 , the conditioning means furthermore comprising any of a ROS scavenger providing means, a calcium channel blockers and phospholipids providing means, a dexamethasone providing means, a barrier gel providing means or a means for providing anti-angeiongic factors or fibroblast manipulation means. 
     
     
         51 . A conditioning system according to  claim 43 , wherein the conditioning system is arranged to distribute a medicine, drug or chemical through a sprinkler