Soft and calcified tissue implants

Abstract

Disclosed herein is processed dermis graft for use in orthopedic surgical procedures. Specifically exemplified herein is a processed dermis graft comprising one or more bone blacks having a groove cut into the surface thereof, wherein said groove is sufficient to accommodate a fixation screw. Also disclosed is a method of processing dermis that results in a dermis derived implant suitable to replace a tendon or ligament in a recipient in need thereof. Other compositions and applications of a dermis derived implant, and methods of manufacture and use, are disclosed.

1 . An implant comprising:
 a) a section of processed soft tissue comprising a first end and a second end;   b) a first bone block attached by pinning to the first end of the processed soft tissue; and   c) a second bone block attached to the second end of the soft tissue;   wherein the first bone block is obtained from a xenogenic source, and the processed soft tissue is obtained from an allogenic source;   wherein each of the bone blocks comprises cortical bone, cancellous bone, or both; and   wherein each of the bone blocks comprises bone that is mineralized, partially demineralized, or fully demineralized.