Coaxial dual function probe and method of use

Abstract

An energy delivery probe for use in tissue ablation and method of use is presented. The energy delivery device has at least a first energy delivery member and a second energy delivery member that have handle members positioned along a longitudinal axis, each handle member having a proximal and distal end. The distal end of the first handle member is releasably coupled to the proximal end of the second handle member and a portion of each member is defined in a coaxially surrounding relationship to each other along the longitudinal axis. The method of using the probe involves identifying a tissue to be ablated, providing the energy delivery probe, inserting at least a portion of the energy delivery probe into the identified tissue, delivering electrical energy through the energy delivery probe to the identified tissue, and ablating the identified tissue such that at least a first ablation zone is formed.

1 . A method of ablating tissue, wherein the method comprises:
 identifying a tissue to be ablated;   providing an energy delivery probe, wherein the energy delivery probe comprises
 at least a first energy delivery member comprising a first handle member and a second energy delivery member comprising a second handle member positioned along a longitudinal axis, each handle member having a proximal end and a distal end, wherein a portion of the distal end of the first handle member is coupled to a portion of the proximal end of the second handle member; 
   inserting at least a portion of the energy delivery probe into the identified tissue; and   delivering electrical energy through the energy delivery probe to the identified tissue in an amount sufficient to ablate the identified tissue such that at least a first ablation zone is formed.   
     
     
         2 . The method of  claim 1 , wherein the method further comprises
 removing the first energy delivery member; and   inserting at least a portion of the first energy delivery member into the identified tissue;   delivering electrical energy through at least one of the first energy delivery member and the second energy delivery member to the identified tissue in an amount sufficient to ablate the identified tissue such that at least a second ablation zone is formed.   
     
     
         3 . The method of  claim 2 , wherein the method further comprises ablating the target tissue such that at least a portion of the first ablation zone overlaps at least a portion of the second ablation zone. 
     
     
         4 . The method of  claim 1 , wherein the method further comprises delivering electrical energy to the identified tissue in an amount sufficient to irreversibly electroporate the identified tissue. 
     
     
         5 . The method of  claim 1 , wherein the method further comprises delivering at least one of bipolar electrical energy and monopolar electrical energy. 
     
     
         6 . The method of  claim 2 , wherein the method further comprises delivering at least one of bipolar electrical energy and monopolar electrical energy. 
     
     
         7 . The method of  claim 1 , wherein the method further comprises switching between delivery of bipolar energy and monopolar energy. 
     
     
         8 . The method of  claim 1 , wherein the method further comprises inserting fluid into the identified tissue through the energy delivery probe. 
     
     
         9 . The method of  claim 1 , wherein the electrical energy is radiofrequency energy. 
     
     
         10 . A method of ablating tissue, wherein the method comprises:
 identifying a tissue to be ablated;   providing, an energy delivery probe, wherein the energy delivery probe comprises
 at least a first energy delivery member comprising a handle member and a second energy delivery member comprising a handle member, wherein the members are disposed along a longitudinal axis, each handle member having a proximal end and a distal end, wherein a portion of the distal end of the first handle member is coupled to a portion of the proximal end of the second handle member, and at least a portion of the first handle member and a portion of the second handle member are disposed in a coaxially surrounding relationship to each other along the longitudinal axis; 
   inserting at least a portion of the energy delivery probe into the identified tissue; and   delivering electrical energy through the energy delivery probe to the identified tissue in an amount sufficient to ablate the identified tissue such that at least a first ablation zone is formed.   
     
     
         11 . An energy delivery probe for use in tissue ablation comprising:
 at least a first energy delivery member comprising a handle member and a second energy delivery member comprising a second handle member, wherein the members are disposed along a longitudinal axis, each handle, member having a proximal end and a distal end, wherein a portion of the distal end of the first handle member is coupled to a portion of the proximal end of the second handle member, and at least a portion of the first handle member and the second handle member are disposed in a coaxially surrounding relationship to each other along the longitudinal axis.   
     
     
         12 . The energy delivery device of  claim 11 , wherein the energy delivery device is bipolar probe. 
     
     
         13 . The energy delivery probe of  claim 11 , wherein at least one of the first energy delivery member and the second energy delivery member comprises a lumen extending from the proximal end to the distal end. 
     
     
         14 . The energy delivery device of  claim 11 , wherein the energy delivery probe comprises an insulating member, and wherein the insulating member is defined in a coaxially surrounding relationship to a portion of the energy delivery probe. 
     
     
         15 . The energy delivery device of  claim 11 , wherein the energy delivery device is configured to deliver radiofrequency energy to the target tissue sufficient to ablate the target tissue. 
     
     
         16 . The energy delivery device of  claim 11 , wherein the energy delivery device is configured to deliver electrical pulses to a target tissue sufficient to irreversibly electroporate the target tissue. 
     
     
         17 . The energy delivery device of  claim 11 , wherein the first energy delivery member and comprises a trocar, and wherein the second energy delivery member comprises a cannula. 
     
     
         18 . The energy delivery device of  claim 11 , wherein the energy delivery member is selected from the group consisting of an RF electrode, a monopolar electrode, and a bipolar electrode. 
     
     
         19 . The energy delivery device of  claim 11 , wherein the energy delivery probe further comprises an array, wherein the array is deployable along a radius of curvature from at least a portion of the energy delivery member. 
     
     
         20 . The energy delivery device of  claim 11 , wherein the energy delivery probe comprises at least two voltage delivery regions.