US2012251548A1PendingUtilityA1
Treatment of Dermatological Pathologies
Est. expiryApr 1, 2031(~4.7 yrs left)· nominal 20-yr term from priority
Inventors:John Simard
A61P 29/00A61K 2039/545A61K 2039/505C07K 16/244C07K 2317/21C07K 16/245C07K 2317/76A61K 2039/54A61P 17/00A61K 39/3955
48
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Claims
Abstract
Skin inflammation in a human subject is reduced by administering to the subject a pharmaceutical composition that includes a pharmaceutically acceptable carrier and a therapeutically effective amount of an agent that selectively binds IL-1α.
Claims
exact text as granted — not AI-modified1 . A method of reducing skin inflammation in a human subject, the method comprising the step of administering to the subject a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an amount of an agent that selectively binds IL-1α effective to reduce skin inflammation in the subject.
2 . The method of claim 1 , wherein the agent is an anti-IL-1α antibody.
3 . The method of claim 2 , wherein the anti-IL-1α antibody is a monoclonal antibody.
4 . The method of claim 3 , wherein the monoclonal antibody is an IgG1.
5 . The method of claim 3 , wherein the monoclonal antibody comprises a complementarity determining region of MABp1.
6 . The method of claim 3 , wherein the monoclonal antibody is MABp1.
7 . The method of claim 1 , wherein the skin inflammation is associated with acne vulgaris.
8 . The method of claim 1 , wherein the skin inflammation is associated with psoriasis vulgaris.Join the waitlist — get patent alerts
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