Hepatocellular carcinoma protein marker, and method for detection of hepatocellular carcinoma using the same

Abstract

A method of detecting hepatocellular carcinoma includes using an isolated protein including an amino acid sequence represented by SEQ ID NO: 1.

1 . A method of detecting hepatocellular carcinoma, comprising:
 using an isolated protein comprising an amino acid sequence represented by SEQ ID NO: 1.   
     
     
         2 . The method of detecting hepatocellular carcinoma according to  claim 1 , wherein the using of the isolated protein includes extracting from a surgically-sampled biological sample. 
     
     
         3 . The method of detecting hepatocellular carcinoma according to  claim 2 , wherein the using of the isolated protein further comprises preparing the biological sample comprising any one kind of a biopsy sample, blood, plasma, serum, and urine. 
     
     
         4 . The method of detecting hepatocellular carcinoma according to  claim 1 , wherein the using of the isolated protein includes verifying phosphorylation of the isolated protein. 
     
     
         5 . The method of detecting hepatocellular carcinoma according to  claim 4 , wherein the using of the isolated protein further includes extracting from a surgically sampled biological sample. 
     
     
         6 . The method of detecting hepatocellular carcinoma according to  claim 5 , wherein the using of the protein marker further comprises preparing the biological sample comprising any one kind of a biopsy sample, blood, plasma, serum, and urine. 
     
     
         7 . The method of detecting hepatocellular carcinoma according to  claim 4 , wherein the verifying phosphorylation of the isolated protein is performed based on measurement of any one of a serine residue, a threonine residue, and a tyrosine residue of the isolated protein for its phosphorylation. 
     
     
         8 . The method of detecting hepatocellular carcinoma according to  claim 7 , wherein the using of the isolated protein comprises extracting the isolated protein from a surgically sampled biological sample. 
     
     
         9 . The method of detecting hepatocellular carcinoma according to  claim 8 , wherein the using of the isolated protein further comprises preparing the biological sample comprising any one kind of a biopsy sample, blood, plasma, serum, and urine.