US2012115847A1PendingUtilityA1

Compounds for the Treatment of Hepatitis C

Assignee: HEWAWASAM PIYASENAPriority: Nov 21, 2007Filed: Jan 19, 2012Published: May 10, 2012
Est. expiryNov 21, 2027(~1.3 yrs left)· nominal 20-yr term from priority
A61P 31/00A61P 31/14C07D 487/04C07D 519/00
40
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Claims

Abstract

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Claims

exact text as granted — not AI-modified
1 . A composition comprising a compound of formula I and a pharmaceutically acceptable carrier 
       
         
           
           
               
               
           
         
         where R 1  is CONR 5 R 6 ; R 2  is 
       
       
         
           
           
               
               
           
         
       
       R 3  is hydrogen, halo, alkyl, alkenyl, hydroxy, benzyloxy, alkoxy, or haloalkoxy; R 4  is cycloalkyl; R 5  is (alkyl)cycloalkylSO 2 ; R 6  is hydrogen; and R 8  is alkyl; or a pharmaceutically acceptable salt thereof. 
     
     
         2 . The composition of  claim 1  where R 4  is cyclohexyl; R 5  is (methyl)cyclopropylSO 2 ; and R 8  is methyl; or a pharmaceutically acceptable salt thereof.

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