US2012095390A1PendingUtilityA1
Generation of Therapeutic Microfoam
Est. expiryMay 26, 2019(expired)· nominal 20-yr term from priority
Inventors:Tariq OsmanSheila Bronwen Shilton-BrownDavid D. WrightAnthony David HarmanTimothy David Boorman
A61P 9/00A61P 9/14B65D 83/62B65D 83/20B05B 7/0037A61K 9/0019B65D 83/14B65D 83/60B65D 83/48B05B 11/02A61K 9/122A61M 5/31A61K 31/08B65D 83/16A61K 9/12B65D 83/58
57
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Claims
Abstract
Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, thus avoiding use of potentially hazardous amounts of nitrogen.
Claims
exact text as granted — not AI-modified1 . A method for producing a microfoam suitable for use in sclerotherapy of blood vessels characterised in that it comprises passing a mixture of a physiologically acceptable blood dispersible gas and an aqueous sclerosant liquid through one or more passages having at least one cross-sectional dimension of from 0.1 to 30 μm, the ratio of gas to liquid being controlled such that a microfoam is produced having a density of between 0.07 g/ml to 0.19 g/ml and has a half-life of at least 2 minutes.
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