Production method of pyrimidine compounds

Abstract

4-amino-6-alkynyloxypyrimidine compounds shown by the formula (V) which has a controlling activity against pests can be produced by the method which comprises the first step which produces a 4-fluoro-6-alkynyloxypyrimidine compound shown by the formula (I) by making a 4,6-difluoropyrimidine compound shown by the formula (II) react with an alcohol compound shown by the formula (III) H—OR 2   (III) in the presence of a tertiary amine; and the second step which produces the 4-amino-6-alkynyloxypyrimidine compound shown by the formula (V) by making the 4-fluoro-6-alkynyloxypyrimidine compound shown by the formula (I) react with an amine compound shown by the formula (IV)

1 . A compound of 4-fluoro-6-alkynyloxypyrimidine compound shown by the formula (I): 
       
         
           
           
               
               
           
         
       
       wherein R 2  represents C3 to C7 alkynyl, and R 3  represents hydrogen or halogen.