US2012022246A1PendingUtilityA1
Magnetic Pigment
Est. expiryJun 8, 2015(expired)· nominal 20-yr term from priority
Inventors:Jorg KleiberThomas WalterHerbert HarttigChristoph LesniakMartin MennigMichael RiedlingHelmut Schmidt
C12Q 1/6806Y10S435/814Y10S428/90C23C 30/00B03C 1/01C03C 3/078C03C 3/111C03C 3/087C03C 3/108C07H 21/00Y10T428/12042Y10T428/2996C03C 3/091C03C 3/105
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Claims
Abstract
Magnetic particles with an outer glass surface being essentially poreless or having pores of a diameter of less then 10 nm as well as ferromagnetic particles with a glass surface are preferentially useful for the isolation of biological material from samples. They provide a quick and reliable purification.
Claims
exact text as granted — not AI-modified1 - 12 . (canceled)
13 . A method for separating a biological material from a fluid containing the biological material comprising:
a) bringing a sample that contains the biological material in a fluid in contact with a magnetic particle, the magnetic particle comprising a magnetic core and an outer glass layer, said outer glass layer completely covers the magnetic core and does not contain boron oxide; and has an outer glass surface, under conditions such that the biological material binds to the glass surface; and thereafter b) separating the bound biological material from the fluid.
14 . The method of claim 13 , wherein said outer glass surface is pore-free.
15 . The method of claim 13 , wherein said outer glass surface has pores with a diameter of less than 10 nm.
16 . The method of claim 13 , wherein the bound biological material is separated from the fluid using a magnetic field.
17 . The method of claim 13 , wherein the particle is not subjected to the influence of a magnetic field before being brought in contact with the sample and is thus able to sediment when brought in contact with the sample.
18 . The method of claim 13 , further comprising eluting said bound nucleic acids from said magnetic particle.Join the waitlist — get patent alerts
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