US2012021081A1PendingUtilityA1

Composition for skin external application containing red pine root extract

Assignee: RHO HO SIKPriority: Feb 27, 2009Filed: Feb 25, 2010Published: Jan 26, 2012
Est. expiryFeb 27, 2029(~2.6 yrs left)· nominal 20-yr term from priority
A61K 8/9767A61Q 19/08A61Q 17/04A61K 2800/782A61Q 19/00
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Claims

Abstract

The present invention relates to a composition for skin external application containing a pine root extract. More specifically, the composition for skin external application according to the present invention contains, as an active ingredient, a pine root extract which shows various effects, including eliminating free radicals, protecting the cell membrane from damage by UV radiation, inhibiting the production of reactive oxygen species caused by UV radiation, inhibiting the reduction in the expression of superoxide dismutase (SOD) and catalase caused by UV radiation, stimulating the production of HSP70 to protect cells, inhibiting MMP-2 biosynthesis caused by UV radiation, inducing the expression of SIRT1 gene that restores DNA damage, and inducing the expression of LMNA1 gene that maintains the structure of the nuclear membrane. Ultimately, the composition of the present invention prevents skin aging.

Claims

exact text as granted — not AI-modified
1 . A composition for skin external application comprising a pine root extract. 
     
     
         2 . The composition of  claim 1 , wherein the composition is used to prevent skin aging. 
     
     
         3 . The composition of  claim 2 , wherein the composition is used to protect the cell membrane from damage caused by UV radiation. 
     
     
         4 . The composition of  claim 2 , wherein the composition is used to protect cells that promote the production of HSP70 protein. 
     
     
         5 . The composition of  claim 2 , wherein the composition is used to inhibit the biosynthesis of MMP-2 caused by UV radiation. 
     
     
         6 . The composition of  claim 2 , wherein the composition is used to induce the expression of SIRT1 gene that restores DNA damage and the expression of LMNA1 gene that maintains the structure of the nuclear membrane. 
     
     
         7 . The composition of  claim 2 , wherein the composition is used to alleviate skin wrinkles. 
     
     
         8 . The composition of  claim 2 , wherein the composition is used to promote skin regeneration.

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