Process for production of orally ingestible composition containing arabinofuranosyl vitexin, and use of the composition

Abstract

A method for producing an orally ingestible composition containing an arabinofuranosyl vitexin and/or a hydrolysate thereof by using Basella alba as a raw material. The product of such method has a sedative effect and a sleep-inducing effect.

1 . A production method for an orally ingestible composition containing an arabinofuranosyl vitexin and/or a hydrolysate thereof, i.e., vitexin, the method comprising using  Basella alba  as a raw material. 
     
     
         2 . A production method for an orally ingestible composition according to  claim 1 , wherein the arabinofuranosyl vitexin is 2″-O-α-D-arabinofuranosyl vitexin. 
     
     
         3 . A production method for an orally ingestible composition according to  claim 1  or  2 , wherein the production method for an orally ingestible composition comprises the steps of: treating  Basella alba  used as the raw material by any one of cutting, fragmentating, and grinding; and performing solution extraction to prepare an extract. 
     
     
         4 . A production method for an orally ingestible composition according to any one of  claims 1  to  3 , wherein the production method for an orally ingestible composition comprises the step of performing solution extraction with ethanol or ethanol having a final concentration of 55% or more to prepare an extract. 
     
     
         5 . A production method for an orally ingestible composition according to any one of  claims 1  to  4 , wherein the production method for an orally ingestible composition comprises the step of purifying the resultant extract using a column after obtaining the extract. 
     
     
         6 . A production method for an orally ingestible composition according to any one of  claims 1  to  5 , wherein the orally ingestible composition contains 2″-O-α-D-arabinofuranosyl vitexin and/or a hydrolysate thereof, i.e., vitexin as en active ingredient and has a sedative activity and/or a sleep-inducing activity. 
     
     
         7 . A food or beverage, comprising an orally ingestible composition obtained by the production method according to any one of  claims 1  to  6 . 
     
     
         8 . A drug, comprising an orally ingestible composition obtained by the production method according to  claim 6 . 
     
     
         9 . A drug, containing 2″-O-α-D-arabinofuranosyl vitexin as an active ingredient and having a sedative activity and/or sleep-inducing activity.