Pregnane glycoside compositions and caralluma extract products and uses thereof

Abstract

Pregnane glycoside or a Caralluma extract including the pregnane glycoside of the present invention can be used for medical purposes and as food additives, such as a treatment of obesity, a reduction of blood glucose, a reduction of blood pressure, a reduction in hip, waist and arm circumferences, a reduction of fat, increase of BMR, a decrease of BMI, an increase of lean body mass, an appetite-suppression and a reduction/elimination of joint pain, anti-aging, a treatment for falling sex drive, the treatment for impotency and an erectile dysfunction, and an enhancement of energy levels.

1 - 55 . (canceled) 
     
     
         56 . A method of at least one treatment selected from the group consisting of a treatment of obesity, a reduction of blood glucose, a reduction of blood pressure, a reduction in hip, waist and arm circumferences, a reduction of fat, increase of basal metabolic rate (BMR), a decrease of body mass index (BMT), an increase of lean body mass, an appetite-suppression and a reduction/elimination of joint pain, anti-aging, a treatment for falling sex drive, a treatment for impotency and an erectile dysfunction, and an enhancement of energy levels, comprising the step of:
 administering to a subject an effective amount of a composition comprising pregnane glycoside for the treatment.   
     
     
         57 . The method of  claim 56 , wherein the pregnane glycoside comprises caratuberside. 
     
     
         58 . The method of  claim 57 , wherein the pregnane glycoside comprises caratuberside and bouceroside, and a ratio of the caratuberside to the bouceroside is from 9:1 to 11:1. 
     
     
         59 . The method of  claim 56 , wherein the composition is a  Caralluma  extract. 
     
     
         60 . The method of  claim 59 , wherein the  Caralluma  extract comprises about 35% to 50% by wt of the pregnane glycoside, and the pregnane glycoside consists essentially of caratuberside and bouceroside. 
     
     
         61 . The method of  claim 56 , wherein the pregnane glycoside is in the form of a pharmaceutically acceptable salt. 
     
     
         62 . The method of  claim 56 , further comprising a pharmaceutically acceptable carrier. 
     
     
         63 . The method of  claim 59 , wherein the  Caralluma  extract further comprises a bitter. 
     
     
         64 . The method of  claim 59 , wherein the composition further comprises at least one second component selected from the group consisting of a fenugreek extract, hydroxyisoleucine, protodioscin, zinc monomethionine, glucosamine, glucosamine with rutin, rutin, bioflavonoid, selenium, a garcinia extract, hydroxycitrate, a green tea extract, saponin glycoside, an ashwagandha extract, a shilajith, coccinia extract containing terpenes, a bitter gourd extract containing bitters, a  Hibiscus Subdarifa  extract containing polyphenols, a cinnamon extract containing polyphenols, a  Commiphora Mukul  extract containing gugulsterones, a liquorice extract containing triphytoestrogen, a red clover extract containing isoflavones, a Hop's flower extract containing triphytoestrogen, a pomegranate extract containing Ellagic acid, and bamboo silica. 
     
     
         65 . The method of  claim 64 , wherein the second component is the  garcinia  extract or hydroxycitrate. 
     
     
         66 . The method of  claim 64 , wherein the second component is glucosamine. 
     
     
         67 . The method of  claim 64 , wherein the second component is glucosamine and rutin. 
     
     
         68 . The method of  claim 64 , wherein the second component is glucosamine, rutin, and chondroitin sulfate. 
     
     
         69 . The method of  claim 64 , wherein the second component is 4-hydroxy-isoleucine. 
     
     
         70 . The method of  claim 64 , wherein the second component comprises the fenugreek extract containing 4-hydroxy-iso-leucine, the coccinia extract containing about 10% terpenes, the bitter gourd extract containing about 8% bitters, and the cinnamon extract containing about 15% polyphenols. 
     
     
         71 . The method of  claim 64 , wherein the second component comprises the fenugreek extract containing about 50% w/w protodioscin. 
     
     
         72 . The method of  claim 64 , wherein the second component comprises the zinc monomethionine, and citrus bioflavonoids with selenium. 
     
     
         73 . The method of  claim 64 , wherein the second component comprises rutin and bamboo silica. 
     
     
         74 . The method of  claim 64 , wherein the second component comprises glucosamine, rutin and bamboo silica. 
     
     
         75 . The method of  claim 64 , wherein the second component is saponin glycoside. 
     
     
         76 . The method of  claim 64 , wherein the second component is the  garcinia  extract or hydroxycitrate, and the at least one treatment is the reduction of fat and the appetite-suppression. 
     
     
         77 . The method of  claim 64 , wherein the second component is saponin glycoside, and the at least one treatment is the treatment for impotency and an erectile dysfunction. 
     
     
         78 . The method of  claim 64 , wherein the second component is the shilajith, and the at least one treatment is the treatment for falling sex drive. 
     
     
         79 . A method of treating obesity and diseases associated therewith in a patient, comprising the step of:
 administering to the patient an effective amount of a composition comprising pregnane glycoside.   
     
     
         80 . The method of  claim 79 , wherein the pregnane glycoside comprises caratuberside. 
     
     
         81 . The method of  claim 80 , wherein the pregnane glycoside comprises caratuberside and bouceroside. 
     
     
         82 . The method of  claim 81 , wherein a ratio of the caratuberside to the bouceroside is from 9:1 to 11:1. 
     
     
         83 . The method of  claim 79 , wherein the composition is a  Caralluma  extract. 
     
     
         84 . The method of  claim 79 , wherein the composition further comprises at least one second component selected from the group consisting of a fenugreek extract, hydroxy-isoleucine, protodioscin, zinc monomethionine, glucosamine, glucosamine with rutin, rutin, bioflavonoid, selenium, a garcinia extract, hydroxycitrate, a green tea extract, saponin glycoside, an ashwagandha extract, a shilajith, coccinia extract containing terpenes, a bitter gourd extract containing bitters, a  Hibiscus Subdarifa  extract containing polyphenols, a cinnamon extract containing polyphenols, a  Commiphora Mukul  extract containing gugulsterones, a liquorice extract containing triphytoestrogen, a red clover extract containing isoflavones, a Hop's flower extract containing triphytoestrogen, a pomegranate extract containing Ellagic acid, and bamboo silica.