US2011230432A1PendingUtilityA1
Compositions and kits for treating influenza
Assignee: ADAMAS PHARMACEUTICALS INCPriority: Mar 13, 2007Filed: May 26, 2011Published: Sep 22, 2011
Est. expiryMar 13, 2027(~0.6 yrs left)· nominal 20-yr term from priority
A61P 31/16A61P 43/00A61P 31/12A61K 31/454A61K 31/7056
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Abstract
Compositions, kits and methods are provided for the treatment or prophylaxis of influenza.
Claims
exact text as granted — not AI-modified1 . A method of preventing or treating influenza comprising administering to a patient a therapeutically effective amount of a combination of first, second and third antiviral agents comprising: a) an M2 inhibitor; b) a second antiviral agent selected from the group consisting of a replication inhibitor, an IMP dehydrogenase inhibitor and an RNA polymerase inhibitor; and c) a neuraminidase inhibitor (NAi); and wherein the combination increases the in vitro sensitivity of one or more strains of an influenza A virus to at least one of the antiviral agents by at least two fold.
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