Cholesterol lowering supplement and low cholesterol egg produced by using the same

Abstract

This invention provides compositions and methods for producing low cholesterol poultry eggs using hypocholesterolemic compounds, cholesterol lowering supplements, and feeds therefrom. The compositions include industrial by-products obtained during production of pravastatin as effective ingredients for lowering the cholesterol content in eggs. The present invention enables the production of eggs with greatly reduced cholesterol content in an economical way. Therefore, the present invention can be considered the first technique suitable for practical use in the production of low cholesterol eggs using statins.

1 . A composition for producing low cholesterol poultry eggs comprising industrial by-products obtained during production of pravastatin as effective ingredients, wherein the pravastatin production involves bioconversion of compactin to pravastatin using microorganisms. 
     
     
         2 . The composition of  claim 1 , wherein the industrial by-products are obtained during production of pravastatin using microorganisms, separation of the pravastatin and/or purification of the pravastatin. 
     
     
         3 . The composition of  claim 1 , wherein the industrial by-products include at least one of compactin, pravastatin and derivatives thereof. 
     
     
         4 . A feed supplement for producing low cholesterol eggs comprising the composition of  claim 1 . 
     
     
         5 . A feed for producing low cholesterol eggs comprising the composition of  claim 1 . 
     
     
         6 . A method for producing low cholesterol eggs comprising administrating to poultry industrial by-products obtained during production of pravastatin as effective ingredients, wherein the pravastatin production involves bioconversion of compactin to pravastatin using microorganisms. 
     
     
         7 . The method of  claim 6 , wherein the industrial by-products are obtained during production of pravastatin using microorganisms, separation of the pravastatin and/or purification of the pravastatin. 
     
     
         8 . The method of  claim 6 , wherein the industrial by-products include at least one of compactin, pravastatin and derivatives thereof. 
     
     
         9 . The method of  claim 6 , wherein the industrial by-products are added in an amount of 0.01 to 10% by weight to a feed and then the feed is administered at least once daily for at least 5 days. 
     
     
         10 . A low cholesterol egg produced by the method of  claim 6 .