Composition for controlling increase in blood glucose

Abstract

The present application describes a composition for blood glucose control containing green tea extracts (GTE) with gallated catechins (GC) and macromolecule to prevent the intestinal absorption of GC.

1 . A composition for blood glucose control containing green tea extracts (GTE) with gallated catechins (GC) and a macromolecule to prevent the intestinal absorption of GC. 
     
     
         2 . The composition according to  claim 1 , wherein the GC comprises at least one of epigallocatechin gallate (EGCG) or epicatechin gallate (ECG). 
     
     
         3 . The composition according to  claim 1 , wherein the macromolecule is polyethylene glycol (PEG), PEG derivatives, PEG copolymer, water-soluble copolymer, methoxy PEG (mPEG) or polypropylene glycol (PPG). 
     
     
         4 . The composition according to  claim 3 , wherein the macromolecule has molecular weight of 1,000-2,000,000 daltons. 
     
     
         5 . A functional food comprising the composition according to  claim 1 . 
     
     
         6 . The functional food according to  claim 5 , wherein the food is a beverage, tablet or powder. 
     
     
         7 . A pharmaceutical composition comprising a blood glucose controlling amount of the composition according to  claim 1 , and a pharmaceutically acceptable excipient thereof. 
     
     
         8 . The pharmaceutical composition according to  claim 7 , wherein the GC comprises EGCG or ECG. 
     
     
         9 . The pharmaceutical composition according to  claim 7 , wherein the macromolecule is PEG, PEG derivatives, PEG copolymer, water-soluble copolymer, methoxy PEG (mPEG) or PPG. 
     
     
         10 . The pharmaceutical composition according to  claim 7 , wherein the macromolecule has a molecular weight of 1,000-50,000 daltons. 
     
     
         11 . A method for controlling blood glucose level in a subject, comprising administering to the subject the composition according to  claim 1 .