US2011182908A1PendingUtilityA1

Diagnostics and Therapeutics for Macular Degeneration-Related Disorders

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Assignee: UNIV IOWA RES FOUNDPriority: Feb 22, 2000Filed: Sep 23, 2010Published: Jul 28, 2011
Est. expiryFeb 22, 2020(expired)· nominal 20-yr term from priority
Inventors:Gregory S. HagemanRobert Mullins
A61P 37/02A61K 51/10C12Q 1/6883G01N 2800/164A61K 38/00A61K 47/46G01N 33/6896A61P 27/02G01N 33/564G01N 2333/4716G01N 33/6893C12Q 2600/158
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Claims

Abstract

The invention relates to methods for treating, preventing and diagnosing macular degeneration-related disorders.

Claims

exact text as granted — not AI-modified
1 . A method for diagnosing, or identifying a predisposition to the development of, a macular degeneration-related disorder in a subject, comprising detecting in a biological sample from the subject an abnormal activity or an abnormal level of at least one complement pathway associated molecule, or an abnormal cellular activity mediated by the complement pathway. 
     
     
         2 .- 19 . (canceled) 
     
     
         20 . A method for treating or preventing the development of a macular degeneration in a subject, comprising providing to the subject an effective amount of a therapeutic agent which modulates an activity or expression level of at least one complement pathway associated molecule, or a cellular activity mediated by the compelement pathway, wherein the subject is suffering from or at risk of developing a macular degeneration-related disorder. 
     
     
         21 .- 37 . (canceled)

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