US2011178274A1PendingUtilityA1

Canine transient receptor potential v2 (ctrpv2) and methods of screening for trpv2 channel modulators

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Assignee: JANSSEN PHARMACEUTICA NVPriority: Mar 7, 2007Filed: Feb 28, 2011Published: Jul 21, 2011
Est. expiryMar 7, 2027(~0.6 yrs left)· nominal 20-yr term from priority
Inventors:Ning QinChristopher FloresMichael P. Neeper
G01N 33/6872G01N 2800/2842G01N 2500/10C07K 14/705
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Claims

Abstract

A recombinant canine TRPV2 channel which has been prepared by cDNA cloning and polymerase chain reaction techniques is disclosed. Expression systems for these channels and an assay using the expression systems are also disclosed. The recombinant TRPV2 channel can be used in assays to evaluate compounds which directly or indirectly interact with or bind to TRPV2 channel.

Claims

exact text as granted — not AI-modified
1 . A substantially purified polypeptide capable of TRPV2 activity and having at least 90% sequence identity to SEQ ID NO: 2. 
     
     
         2 . The substantially purified polypeptide of  claim 1  comprising SEQ ID NO: 2.

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