US2011165177A1PendingUtilityA1

Methods of Modulating Immunity

Assignee: BRIGHAM & WOMENS HOSPITALPriority: Nov 14, 2003Filed: Dec 30, 2010Published: Jul 7, 2011
Est. expiryNov 14, 2023(expired)· nominal 20-yr term from priority
A61P 3/10A61P 37/06A61P 37/02A61P 37/00A61P 27/14A61P 29/00A61P 25/00A61P 19/02A61P 1/04A61P 17/06A61K 2039/505C07K 2317/54C07K 16/2809A61K 2039/542
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Claims

Abstract

The invention provides novel methods of administering anti-CD3 antibodies, e.g., via oral or mucosal delivery. The invention also provides methods of treating, preventing, or delaying the onset of autoimmune disorders by oral or mucosal administration of anti-CD3 antibodies. Finally, the invention provides compositions including anti-CD3 antibodies, suitable for oral or mucosal administration.

Claims

exact text as granted — not AI-modified
1 . A method of treating, preventing, or delaying the onset of an autoimmune disease in a subject, the method comprising administering to the subject an anti-CD3 antibody, wherein the administering is oral or mucosal.

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