Il-17 receptor like molecules and uses thereof

Abstract

The present invention provides for IL-17 receptor like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, agonists and antagonists (including selective binding agents), and methods for producing IL-17 receptor like polypeptides. Also provided for are methods for treatment, diagnosis, amelioration, or prevention of diseases with IL-17 receptor like polypeptides.

1 . An isolated antibody, or antigen binding fragment thereof, that specifically binds a polypeptide consisting of amino acids 14 through 350 of SEQ ID NO: 5. 
     
     
         2 . The antibody of  claim 1 , wherein said antibody is a monoclonal antibody. 
     
     
         3 . The antibody of  claim 1 , wherein said antibody is a human monoclonal antibody. 
     
     
         4 . The antibody of  claim 1 , wherein said antibody is a humanized monoclonal antibody. 
     
     
         5 . The antibody of  claim 1 , wherein said antibody is a chimeric monoclonal antibody. 
     
     
         6 . An isolated antibody, or antigen binding fragment thereof, that specifically binds a polypeptide consisting of amino acids 14 through 350 of SEQ ID NO: 5 and inhibits the binding of SEQ ID NO: 23. 
     
     
         7 . The antibody of  claim 6 , wherein said antibody is a monoclonal antibody. 
     
     
         8 . The antibody of  claim 6 , wherein said antibody is a human monoclonal antibody. 
     
     
         9 . The antibody of  claim 6 , wherein said antibody is a humanized monoclonal antibody. 
     
     
         10 . The antibody of  claim 6 , wherein said antibody is a chimeric monoclonal antibody.