US2011152301A1PendingUtilityA1

Compounds that Inhibit HIV Particle Formation

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Assignee: Univ Virginia Patent FoundPriority: Feb 4, 2004Filed: Dec 22, 2010Published: Jun 23, 2011
Est. expiryFeb 4, 2024(expired)· nominal 20-yr term from priority
Inventors:David RekoshMarie-Louise Hammarskjöld
C07D 237/24C07D 495/04G01N 2333/163C07D 471/04A61P 31/18C07D 239/38G01N 2500/10C07D 215/54C07D 277/56C07D 239/94G01N 2333/161G01N 33/56988
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Claims

Abstract

The present invention describes novel methods of identifying compounds which inhibit HIV particle formation and Rev-dependent HIV production. The present invention also provides methods and compounds for inhibiting HIV particle formation and or treating patients infected with HIV.

Claims

exact text as granted — not AI-modified
1 - 24 . (canceled) 
     
     
         25 . A method of inhibiting HIV replication, said method comprising contacting a cell comprising HIV with an effective amount of a compound selected from the group consisting of: 
       
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
         
           
           
               
               
           
         
       
     
     
         26 . The method of  claim 25 , wherein said compound inhibits REV function. 
     
     
         27 . The method of  claim 25 , wherein HIV virion production is dependent on Rev protein expression.

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