US2011130576A1PendingUtilityA1

Process for producing (z)-1-phenyl-1-(n,n-diethylaminocarbonyl)-2-phthalimidomethylcyclopropane

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Assignee: SUMITOMO CHEMICAL COPriority: Jan 28, 2005Filed: Feb 10, 2011Published: Jun 2, 2011
Est. expiryJan 28, 2025(expired)· nominal 20-yr term from priority
Inventors:Yoshihide NiimotoHiroharu KumazawaKoh Kawami
C07D 209/48A61P 25/24C07D 307/93A61K 31/343A61K 31/34
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Claims

Abstract

The present invention provides a process for producing (Z)-1-phenyl-1-(N,N-diethylaminocarbonyl)-2-phthalimidomethylcyclopropane, which includes reacting (Z)-1-phenyl-1-(N,N-diethylaminocarbonyl)-2-hydroxymethylcyclopropane with an orthoester and a brønsted acid, and reacting the reaction product with a phthalimidating agent; and a process for producing (Z)-1-phenyl-1-(N,N-diethylaminocarbonyl)-2-aminomethylcyclopropane hydrochloride through the above process.

Claims

exact text as granted — not AI-modified
1 . An iminium salt of the formula (I) 
       
         
           
           
               
               
           
         
       
       wherein A -  represents conjugated base of a brønsted acid. 
     
     
         2 . The iminium salt according to  claim 1 , wherein A- is CH3SO3-.

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